Background Vaso-occlusive crisis (VOC) is one of the most frequent causes of emergency
visits and admission in children with sickle cell disease (SCD). Objectives This study aims to …

Objectives To assess the efficacy and adverse events linked to the utilization of fentanyl for
perioperative pain management in dentistry. Methods This systematic review of randomized …

Although anatomical and structural similarities between the skin of minipigs and humans are
often reported, few percutaneous pharmacokinetic studies have been conducted in minipigs …

To the Editor: Episodic breathlessness is a common and distressing symptom in advanced
malignant and non-malignant disease. There is good evidence for the systemic use of …

Reports of IN fentanyl were considered for inclusion if they had prehospital treatment of pain
as an endpoint, were evaluated by validated pain score or as effect on analgesic …

Introduction Removal of mandibular third molars surgically is one of the most frequently
performed oral surgical procedures which are often accompanied with post-operative pain …

Purpose The aims of this study were to explore the efficacy of intranasal fentanyl
spray*(INFS) 400 μg to evaluate 12-week tolerability of the nasal mucosa and to explore …

Due to the presence of large surfaces and high blood supply, drug delivery through the
nasal route of administration is the appropriate route to administrate drugs with rapid onsets …

We present the case of a 3-month-old girl who had unrepaired Tetralogy of Fallot who
presented to the emergency department with an acute hypoxic episode. The patient was …

Background: Although acetaminophen is used to reduce pain after breast reduction or
augmentation surgery, pain during the removal of the surgical drains is typically not …