Sepsis-associated acute kidney injury

CL Manrique-Caballero… - Critical Care …, 2021 - criticalcare.theclinics.com
Sepsis-associated acute kidney injury (S-AKI) is a common, life-threatening complication in
hospitalized and critically ill patients. S-AKI increases in-hospital mortality 6-fold to 8-fold, 1 …

Management of acute kidney injury: core curriculum 2018

PK Moore, RK Hsu, KD Liu - American Journal of Kidney Diseases, 2018 - Elsevier
Acute kidney injury (AKI) is a heterogeneous disorder that is common in hospitalized
patients and associated with short-and long-term morbidity and mortality. When AKI is …

Acute kidney injury in SARS-CoV-2 infected patients

V Fanelli, M Fiorentino, V Cantaluppi, L Gesualdo… - Critical Care, 2020 - Springer
Background Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the
pathogen responsible of atypical pneumonia that has affected more than 330,000 people …

Cardiac and vascular surgery–associated acute kidney injury: the 20th international consensus conference of the ADQI (acute disease quality initiative) group

MK Nadim, LG Forni, A Bihorac, C Hobson… - Journal of the …, 2018 - Am Heart Assoc
Methods ADQI (Acute Disease Quality Initiative) is an ongoing process that produces
evidence‐based recommendations on the diagnosis, prevention, and management of AKI …

Biomarkers of drug-induced kidney toxicity

BR Griffin, S Faubel, CL Edelstein - Therapeutic drug monitoring, 2019 - journals.lww.com
Blood urea nitrogen and serum creatinine are imperfect markers of kidney function because
they are influenced by many renal and nonrenal factors independent of kidney function. A …

The nuclear receptor ESRRA protects from kidney disease by coupling metabolism and differentiation

P Dhillon, J Park, CH Del Pozo, L Li, T Doke, S Huang… - Cell metabolism, 2021 - cell.com
Kidney disease is poorly understood because of the organ's cellular diversity. We used
single-cell RNA sequencing not only in resolving differences in injured kidney tissue cellular …

Management of patients at risk of acute kidney injury

J Vanmassenhove, J Kielstein, A Jörres, W Van Biesen - The lancet, 2017 - thelancet.com
Acute kidney injury (AKI) is a multifaceted syndrome that occurs in different settings. The
course of AKI can be variable, from single hit and complete recovery, to multiple hits …

Kidney physiology and pathophysiology during heat stress and the modification by exercise, dehydration, heat acclimation and aging

CL Chapman, BD Johnson, MD Parker, D Hostler… - Temperature, 2021 - Taylor & Francis
The kidneys' integrative responses to heat stress aid thermoregulation, cardiovascular
control, and water and electrolyte regulation. Recent evidence suggests the kidneys are at …

Advances in the study of subclinical AKI biomarkers

C Zou, C Wang, L Lu - Frontiers in Physiology, 2022 - frontiersin.org
Acute kidney injury (AKI) is a prevalent and serious illness in all clinical departments, with a
high morbidity and death rate, particularly in intensive care units, where prevention and …

Mechanisms underlying increased TIMP2 and IGFBP7 urinary excretion in experimental AKI

ACM Johnson, RA Zager - Journal of the American Society of …, 2018 - journals.lww.com
Background Recent clinical data support the utility/superiority of a new AKI biomarker
(“NephroCheck”), the arithmetic product of urinary TIMP× IGFBP7 concentrations. However …