Airway deposition and airway effects of antiasthma drugs delivered from metered-dose inhalers

R Pauwels, S Newman… - European Respiratory …, 1997 - Eur Respiratory Soc
Many different metered-dose inhalation devices are becoming available for the treatment of
airway diseases. Each of these inhalers differs in its delivery characteristics. An assessment …

Drug delivery systems

DH Robinson, JW Mauger - American journal of hospital …, 1991 - academic.oup.com
New and emerging drug delivery systems for traditional drugs and the products of
biotechnology are discussed, and the role of the pharmacist in ensuring the appropriate use …

[图书][B] Inhalation aerosols: physical and biological basis for therapy

AJ Hickey, HM Mansour - 2019 - books.google.com
Inhalation aerosols continue to be the basis for successful lung therapy for several diseases,
with therapeutic strategies and the range of technology significantly evolving in recent years …

[图书][B] Particulate interactions in dry powder formulation for inhalation

XM Zeng, GP Martin, C Marriott - 2000 - taylorfrancis.com
Interactions between drug particulates are crucial in determining drug dispersion and
deaggregation, and ultimately delivery efficiency. This book combines principles established …

Disposable jet nebulizers: how reliable are they?

GF Alvine, P Rodgers, KM Fitzsimmons, RC Ahrens - Chest, 1992 - Elsevier
We studied the frequency of malfunction, variability in rate of nebulization, and effect of this
variability on aerosol particle size of eight disposable jet nebulizer models produced by six …

[HTML][HTML] Dynamics of aerosol size during inhalation: hygroscopic growth of commercial nebulizer formulations

AE Haddrell, JF Davies, REH Miles, JP Reid… - International journal of …, 2014 - Elsevier
The size of aerosol particles prior to, and during, inhalation influences the site of deposition
within the lung. As such, a detailed understanding of the hygroscopic growth of an aerosol …

High-performance liquid chromatographic assay for the simultaneous determination of ipratropium bromide, fenoterol, salbutamol and terbutaline in nebulizer solution

GA Jacobson, GM Peterson - Journal of pharmaceutical and biomedical …, 1994 - Elsevier
A reversed-phase ion-pair high-performance liquid chromatography assay was developed
for the simultaneous determination of ipratropium bromide, fenoterol hydrobromide …

In vivo pharmacological characterization of TD-4208, a novel lung-selective inhaled muscarinic antagonist with sustained bronchoprotective effect in experimental …

MT Pulido-Rios, A McNamara, GP Obedencio… - … of Pharmacology and …, 2013 - ASPET
Tiotropium is currently the only once-daily, long-acting muscarinic antagonist (LAMA)
approved in the United States and other countries for the treatment of chronic obstructive …

[图书][B] Biomedical nanosensors

JM Irudayaraj - 2012 - books.google.com
This book draws together recent data on both cytoplasmic and flagellar dyneins and the
proteins they interact with, to give the reader a clear picture of what is currently known about …

Dose-response evaluation of levalbuterol versus racemic albuterol in patients with asthma

DA Handley, D Tinkelman, M Noonan… - Journal of …, 2000 - Taylor & Francis
Albuterol, in all marketed forms, is sold as a racemate, composed of a 50: 50 mixture of (R)-
and (S)-isomers. Racemic albuterol and the single isomer version (R)-albuterol …