Screening for Coronary Artery Disease in Cancer Survivors: JACC: CardioOncology State-of-the-Art Review

R Velusamy, M Nolan, A Murphy, P Thavendiranathan… - Cardio Oncology, 2023 - jacc.org
Coronary artery disease (CAD) is an important contributor to the cardiovascular burden in
cancer survivors. This review identifies features that could help guide decisions about the …

Genomic aging, clonal hematopoiesis, and cardiovascular disease

P Natarajan - Arteriosclerosis, thrombosis, and vascular biology, 2023 - Am Heart Assoc
Chronologic age is the dominant risk factor for coronary artery disease but the features of
aging promoting coronary artery disease are poorly understood. Advances in human …

Priorities in Cardio-Oncology Basic and Translational Science: GCOS 2023 Symposium Proceedings: JACC: CardioOncology State-of-the-Art Review

FN Salloum, CG Tocchetti, P Ameri, H Ardehali… - Cardio Oncology, 2023 - jacc.org
Despite improvements in cancer survival, cancer therapy–related cardiovascular toxicity has
risen to become a prominent clinical challenge. This has led to the growth of the burgeoning …

Cardiovascular disease and cancer: shared risk factors and mechanisms

NS Wilcox, U Amit, JB Reibel, E Berlin… - Nature Reviews …, 2024 - nature.com
Cardiovascular disease (CVD) and cancer are among the leading causes of morbidity and
mortality globally, and these conditions are increasingly recognized to be fundamentally …

A high hematopoietic cell transplantation comorbidity Index (HCT-CI) does not impair outcomes after non-myeloablative allogeneic stem cell transplantation in acute …

D Backhaus, D Brauer, R Pointner, L Bischof… - Bone Marrow …, 2023 - nature.com
For most acute myeloid leukemia (AML) patients an allogeneic hematopoietic stem cell
transplantation (HSCT) offers the highest chance of cure. The introduction of less toxic non …

Bidirectional relationship between cancer and heart failure: insights on circulating biomarkers

M Chianca, G Panichella, I Fabiani… - Frontiers in …, 2022 - frontiersin.org
Cancer and heart failure are the two leading causes of death in developed countries. These
two apparently distinct clinical entities share similar risk factors, symptoms, and …

Cancer therapy's impact on lipid metabolism: Mechanisms and future avenues

R Bhatnagar, NM Dixit, EH Yang… - Frontiers in …, 2022 - frontiersin.org
Atherosclerotic cardiovascular disease is a growing threat among cancer patients. Not
surprisingly, cancer-targeting therapies have been linked to metabolic dysregulation …

Thrombosis in acute myeloid leukemia: pathogenesis, risk factors and therapeutic challenges

M Olivi, F Di Biase, G Lanzarone, G Arrigo… - … Treatment Options in …, 2023 - Springer
Opinion statement Prophylaxis and treatment of thrombosis in leukemic patients still
represent a major challenge with several clinical questions yet to be solved. Indeed, the …

Social Determinants of Health in Cardio-Oncology: Multi-Level Strategies to Overcome Disparities in Care: JACC: CardioOncology State-of-the-Art Review

F Osei Baah, S Sharda, K Davidow, S Jackson… - Cardio Oncology, 2024 - jacc.org
Addressing the need for more equitable cardio-oncology care requires attention to existing
disparities in cardio-oncologic disease prevention and outcomes. This is particularly …

Inhibiting AGTR1 reduces AML burden and protects the heart from cardiotoxicity in mouse models

Y Pan, C Wang, WX Zhou, Y Shi, XD Meng… - Science Translational …, 2024 - science.org
Clinical treatment of acute myeloid leukemia (AML) largely relies on intensive
chemotherapy. However, the application of chemotherapy is often hindered by cardiotoxicity …