FHL1 as a novel prognostic biomarker and correlation with immune infiltration levels in lung adenocarcinoma

J Zhang, H Li, M Guo, J Zhang, G Zhang, N Sun… - …, 2023 - Taylor & Francis
Aim: We aimed to examine the effect of FHL1 in the diagnosis and prognosis of non-small-
cell lung cancer and its relationship with tumor-infiltrating immune cells. Methods: FHL1 …

A multi‐omic study reveals BTG2 as a reliable prognostic marker for early‐stage non‐small cell lung cancer

S Shen, R Zhang, Y Guo, E Loehrer, Y Wei… - Molecular …, 2018 - Wiley Online Library
B‐cell translocation gene 2 (BTG2) is a tumour suppressor protein known to be
downregulated in several types of cancer. In this study, we investigated a potential role for …

Prognostic value of aberrantly expressed methylation gene profiles in lung squamous cell carcinoma: A study based on The Cancer Genome Atlas

C Gao, J Zhuang, C Zhou, K Ma, M Zhao… - Journal of cellular …, 2019 - Wiley Online Library
Currently, research on genome‐scale epigenetic modifications for studying the
pathogenesis of lung cancer is lacking. Aberrant DNA methylation, as the most common and …

[HTML][HTML] Expression signature and role of miR-30d-5p in non-small cell lung cancer: a comprehensive study based on in silico analysis of public databases and in vitro …

L Gao, R He, H Wu, T Zhang, H Liang, Z Ye… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: The purpose of this study was to probe the clinico-pathological
significance and the underlying mechanism of miR-30d-5p expression in non-small cell lung …

Multiomics analysis on DNA methylation and the expression of both messenger RNA and microRNA in lung adenocarcinoma

Z Yang, B Liu, T Lin, Y Zhang, L Zhang… - Journal of Cellular …, 2019 - Wiley Online Library
Lung adenocarcinoma (LUAD) poses a significant threat to public health worldwide, while
the genetic and epigenetic abnormalities involved in the oncogenesis of LUAD remains …

[HTML][HTML] Methylated DNA/RNA in body fluids as biomarkers for lung cancer

Y Lu, SSL Li, SSG Zhu, YYB Gong, JJ Shi… - Biological Procedures …, 2017 - Springer
DNA/RNA methylation plays an important role in lung cancer initiation and progression.
Liquid biopsy makes use of cells, nucleotides and proteins released from tumor cells into …

[HTML][HTML] Clinical significance of miR-210 and its prospective signaling pathways in non-small cell lung cancer: evidence from gene expression omnibus and the cancer …

R He, W Cen, J Cen, W Cen, J Li, M Li, T Gan… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Since the function of microRNA (miR)-210 in non-small cell lung cancer
(NSCLC) remains unclear, we aimed to explore the clinical significance of miR-210 in …

[HTML][HTML] CancerNet: a unified deep learning network for pan-cancer diagnostics

S Gore, RK Azad - BMC bioinformatics, 2022 - Springer
Background Despite remarkable advances in cancer research, cancer remains one of the
leading causes of death worldwide. Early detection of cancer and localization of the tissue of …

[HTML][HTML] Loss of miR-145-5p causes ceruloplasmin interference with PHD-iron axis and HIF-2α stabilization in lung adenocarcinoma-mediated angiogenesis

YM Tsai, KL Wu, YY Chang, WA Chang… - International Journal of …, 2020 - mdpi.com
For decades, lung cancer has been the leading cause of cancer-related death worldwide.
Hypoxia-inducible factors (HIFs) play critical roles in mediating lung cancer development …

[HTML][HTML] Construction and analysis of a ceRNA network reveals potential prognostic markers in colorectal cancer

L Guo, G Yang, Y Kang, S Li, R Duan, L Shen… - Frontiers in …, 2020 - frontiersin.org
Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths worldwide
and is derived from an accumulation of genetic and epigenetic changes. This study explored …