[HTML][HTML] Prognostic and predictive biomarkers post curative intent therapy

R Feldman, ES Kim - Annals of Translational Medicine, 2017 - ncbi.nlm.nih.gov
Large-scale screening trials have demonstrated that early diagnosis of lung cancer results in
a significant reduction in lung cancer mortality. Despite improvements in detecting more lung …

HLA-DQB1 expression on tumor cells is a novel favorable prognostic factor for relapse in early-stage lung adenocarcinoma

L Zhang, M Li, B Deng, N Dai, Y Feng… - Cancer Management …, 2019 - Taylor & Francis
Background: Postoperative recurrence is the main cause of a poor prognosis in early-stage
lung adenocarcinoma (LUAD). Factors that can predict recurrence risk are critically needed …

HOXA9 methylation and blood vessel invasion in FFPE tissues for prognostic stratification of stage I lung adenocarcinoma patients

D Lissa, T Ishigame, R Noro, MJ Tucker, V Bliskovsky… - Lung Cancer, 2018 - Elsevier
Objectives Surgery with curative intent is the standard treatment for stage I lung
adenocarcinoma. However, disease recurrence occurs in a third of patients. Prognostic …

miR‐130A as a diagnostic marker to differentiate malignant mesothelioma from lung adenocarcinoma in pleural effusion cytology

R Cappellesso, M Galasso, L Nicolè… - Cancer …, 2017 - Wiley Online Library
BACKGROUND Malignant pleural mesothelioma is a rare tumor with a dismal prognosis,
usually presenting with recurrent effusions. However, the majority of malignant pleural …

[HTML][HTML] Benefits from Adjuvant Chemotherapy in Patients with Resected Non-Small Cell Lung Cancer: Possibility of Stratification by Gene Amplification of ACTN4 …

T Tozuka, R Noro, M Seike, K Honda - Cancers, 2022 - mdpi.com
Simple Summary The establishment of biomarkers that can identify individuals at high risk of
early recurrence after surgery will be an important issue in decision-making for perioperative …

[HTML][HTML] The prognostic value of homeobox A9 (HOXA9) methylation in solid tumors: a systematic review and meta-analysis

H Cai, ZB Ke, RN Dong, H Chen, F Lin… - Translational cancer …, 2021 - ncbi.nlm.nih.gov
Background The prognosis of homeobox A9 (HOXA9) methylation have been assessed in a
variety of cancers; nevertheless, the results remain undetermined due to discrete outcome …

[HTML][HTML] Distance in cancer gene expression from stem cells predicts patient survival

M Riester, HJ Wu, A Zehir, M Gönen, AL Moreira… - PLoS …, 2017 - journals.plos.org
The degree of histologic cellular differentiation of a cancer has been associated with
prognosis but is subjectively assessed. We hypothesized that information about tumor …

Tumor suppressor gene DLC1: Its modifications, interactive molecules, and potential prospects for clinical cancer application

G Ren, G Li - International Journal of Biological Macromolecules, 2021 - Elsevier
Deleted in liver cancer 1 (DLC1) is a recognized tumor suppressor gene that negatively
regulates Rho family proteins by hydrolyzing the active GTP-bound state to its inactive GDP …

MicroRNAs in non-small cell lung cancer invasion and metastasis: from the perspective of the radiation oncologist

V Verma, T Lautenschlaeger - Expert Review of Anticancer …, 2016 - Taylor & Francis
ABSTRACT Introduction: MicroRNAs (miRs), small sequences of RNA regulating various
cellular processes, are implicated to play major roles in cancer. Herein, we discuss the …

[HTML][HTML] The prognostic impact of circulating homeobox A9 methylated DNA in advanced non-small cell lung cancer

SWC Wen, RF Andersen, TF Hansen… - Translational Lung …, 2021 - ncbi.nlm.nih.gov
Background The homeobox A9 gene encodes a transcription factor, and aberrantly
methylated homeobox A9 in the circulation has been suggested as a prognostic marker in …