Research progress of biodegradable magnesium-based biomedical materials: A review

J Wang, J Dou, Z Wang, C Hu, H Yu, C Chen - Journal of Alloys and …, 2022 - Elsevier
This review covers several aspects of the rapid development of magnesium (Mg) alloys from
the owned properties and corrosion mechanism to the effect of optimization of mechanical …

Biodegradable bone implants in orthopedic applications: a review

G Chandra, A Pandey - Biocybernetics and Biomedical Engineering, 2020 - Elsevier
A biologically-validated biodegradable material must comfortably stay in the physiological
environment it is placed in, before finally disappearing over the intended period of time with …

Fracture healing as a postnatal developmental process: molecular, spatial, and temporal aspects of its regulation

LC Gerstenfeld, DM Cullinane… - Journal of cellular …, 2003 - Wiley Online Library
Fracture healing is a specialized postnatal repair process that recapitulates aspects of
embryological skeletal development. While many of the molecular mechanisms that control …

Control of osteoblast function and regulation of bone mass

S Harada, GA Rodan - Nature, 2003 - nature.com
The skeleton is an efficient'servo'(feedback-controlled/steady-state) system that continuously
integrates signals and responses which sustain its functions of delivering calcium while …

Angiogenesis and bone repair

RAD Carano, EH Filvaroff - Drug discovery today, 2003 - Elsevier
The intimate connection, both physical and biochemical, between blood vessels and bone
cells has long been recognized. Genetic, biochemical, and pharmacological studies have …

Development of a nanostructured DNA delivery scaffold via electrospinning of PLGA and PLA–PEG block copolymers

YK Luu, K Kim, BS Hsiao, B Chu… - Journal of controlled …, 2003 - Elsevier
The present work utilizes electrospinning to fabricate synthetic polymer/DNA composite
scaffolds for therapeutic application in gene delivery for tissue engineering. The scaffolds …

Recent development of polymer nanofibers for biomedical and biotechnological applications

Y Zhang, CT Lim, S Ramakrishna… - Journal of materials …, 2005 - Springer
Research in polymer nanofibers has undergone significant progress in the last one decade.
One of the main driving forces for this progress is the increasing use of these polymer …

Bone regeneration and stem cells

K Arvidson, BM Abdallah, LA Applegate… - Journal of cellular …, 2011 - Wiley Online Library
Introduction• Bone fracture healing and healing problems• Biomaterial scaffolds and tissue
engineering in bone formationBone tissue engineeringBiomaterial scaffoldsSynthetic …

Wnt signaling in osteoblasts and bone diseases

JJ Westendorf, RA Kahler, TM Schroeder - Gene, 2004 - Elsevier
Recent revelations that the canonical Wnt signaling pathway promotes postnatal bone
accrual are major advances in our understanding of skeletal biology and bring tremendous …

Fracture healing physiology and the quest for therapies for delayed healing and nonunion

P Kostenuik, FM Mirza - Journal of Orthopaedic Research®, 2017 - Wiley Online Library
Delayed healing and nonunion of fractures represent enormous burdens to patients and
healthcare systems. There are currently no approved pharmacological agents for the …