[HTML][HTML] Metabolomics as a powerful tool for diagnostic, pronostic and drug intervention analysis in COVID-19

C Bruzzone, R Conde, N Embade, JM Mato… - Frontiers in molecular …, 2023 - frontiersin.org
COVID-19 currently represents one of the major health challenges worldwide. Albeit its
infectious character, with onset affectation mainly at the respiratory track, it is clear that the …

[HTML][HTML] Oligosaccharides as potential regulators of gut microbiota and intestinal health in post-covid-19 management

KL Cheong, S Chen, B Teng, S Veeraperumal… - Pharmaceuticals, 2023 - mdpi.com
The COVID-19 pandemic has had a profound impact worldwide, resulting in long-term
health effects for many individuals. Recently, as more and more people recover from COVID …

[HTML][HTML] Metabolomics markers of COVID-19 are dependent on collection wave

HM Lewis, Y Liu, CF Frampas, K Longman, M Spick… - Metabolites, 2022 - mdpi.com
The effect of COVID-19 infection on the human metabolome has been widely reported, but to
date all such studies have focused on a single wave of infection. COVID-19 has generated …

[HTML][HTML] Multi-omics reveals mechanisms of partial modulation of COVID-19 dysregulation by glucocorticoid treatment

M Spick, A Campbell, I Baricevic-Jones… - International journal of …, 2022 - mdpi.com
Treatments for COVID-19 infections have improved dramatically since the beginning of the
pandemic, and glucocorticoids have been a key tool in improving mortality rates. The UK's …

[HTML][HTML] Integrated microbiome and metabolome analysis reveals the potential therapeutic mechanism of Qing-Fei-Pai-Du decoction in mice with coronavirus-induced …

G Wu, W Zhang, N Zheng, X Zu, S Tian… - Frontiers in Cellular …, 2022 - frontiersin.org
Current studies have shown that gut microbiota may be closely related to the severity of
coronavirus disease 2019 (COVID-19) by regulating the host immune response. Qing-Fei …

Dynamic modulations of sphingolipids and glycerophospholipids in COVID‐19

M Kurano, K Okamoto, D Jubishi… - Clinical and …, 2022 - Wiley Online Library
Background A heterogeneous clinical phenotype is a characteristic of coronavirus disease
2019 (COVID‐19). Therefore, investigating biomarkers associated with disease severity is …

[HTML][HTML] Simultaneous quantitation and discovery (SQUAD) analysis: combining the best of targeted and untargeted mass spectrometry-based metabolomics

B Amer, RR Deshpande, SS Bird - Metabolites, 2023 - mdpi.com
Untargeted and targeted approaches are the traditional metabolomics workflows acquired
for a wider understanding of the metabolome under focus. Both approaches have their …

[HTML][HTML] Combining semi-targeted metabolomics and machine learning to identify metabolic alterations in the serum and urine of hospitalized patients with COVID-19

G Baiges-Gaya, S Iftimie, H Castañé… - Biomolecules, 2023 - mdpi.com
Viral infections cause metabolic dysregulation in the infected organism. The present study
used metabolomics techniques and machine learning algorithms to retrospectively analyze …

Chewing the fat: How lipidomics is changing our understanding of human health and disease in 2022

C Géhin, SJ Fowler, DK Trivedi - Analytical Science Advances, 2023 - Wiley Online Library
Lipids are biological molecules that play vital roles in all living organisms. They perform
many cellular functions, such as 1) forming cellular and subcellular membranes, 2) storing …

Mass spectrometric approaches in discovering lipid biomarkers for COVID‐19 by lipidomics: Future challenges and perspectives

SG B. Gowda, C Shekhar, D Gowda… - Mass Spectrometry …, 2023 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) has emerged as a global health threat and
has rapidly spread worldwide. Significant changes in the lipid profile before and after COVID …