Triple-negative breast cancer (TNBC) is one of the deadliest subtypes of breast cancer (BC)
for its high aggressiveness, heterogeneity, and hypoxic nature. Based on biological and …

Triple-negative breast cancer (TNBC) is usually the most malignant and aggressive
mammary epithelial tumor characterized by the lack of expression for estrogen receptors …

Triple-negative breast cancer (TNBC) lacks specific regimens for targeted therapy. Repeat
chemotherapy promotes the evolution of TNBC into highly chemo-resistant tumors that …

In this study we conducted the first investigation to assess the efficacy of a novel therapeutic
antibody developed to target annexin-A1 (ANXA1). ANXA1 is an immunomodulatory protein …

Odorant receptors, traditionally associated with olfaction as chemoreceptors, have been
increasingly recognized for their presence and diverse functions in various non-nasal …

Abstract Annexin A1 (ANXA1) is widely expressed in a variety of body tissues and cells and
is also involved in tumor development through multiple pathways. The invasion, metastasis …

Sex-driven immune differences can affect tumor progression and the landscape of the tumor
microenvironment. Deeper understanding of these differences in males and females can …

The manuscript describes the development of zein nanoparticles containing paclitaxel (PTX)
and the bromo-and extra-terminal domain inhibitor (S)-tertbutyl2-(4-(4-chlorophenyl)-2, 3, 9 …

Abstract Although annexin A1 (ANXA1), a 37 kDa phospholipid‑binding anti‑inflammatory
protein expressed in various tissues and cell types, has been investigated extensively for its …

Background Dysregulated macrophages are important causes of Atherosclerosis (AS)
formation and increased plaque instability, but the heterogeneity of these plaques and the …