A picture guide to cancer progression and monotonic accumulation models: evolutionary assumptions, plausible interpretations, and alternative uses

R Diaz-Uriarte - arXiv preprint arXiv:2312.06824, 2023 - arxiv.org
Cancer progression and monotonic accumulation models were developed to discover
dependencies in the irreversible acquisition of binary traits from cross-sectional data. They …

Taming numerical imprecision by adapting the KL divergence to negative probabilities

S Pfahler, P Georg, R Schill, M Klever… - Statistics and …, 2024 - Springer
Abstract The Kullback–Leibler (KL) divergence is frequently used in data science. For
discrete distributions on large state spaces, approximations of probability vectors may result …

Overcoming Observation Bias for Cancer Progression Modeling

R Schill, M Klever, A Lösch, YL Hu, S Vocht… - … on Research in …, 2024 - Springer
Cancers evolve by accumulating genetic alterations, such as mutations and copy number
changes. The chronological order of these events is important for understanding the …

Overcoming Observation Bias for Cancer Progression Modeling

N Beerenwinkel - Research in Computational Molecular Biology: 28th … - books.google.com
Cancers evolve by accumulating genetic alterations, such as mutations and copy number
changes. The chronological order of these events is important for understanding the …