At present, the standard practices for home-based assessments of abnormal movements in
Parkinson's disease (PD) are based either on subjective tools or on objective measures that …

Circadian rhythm is manifested by the behavioral and physiological changes from day to
night, which is controlled by the pacemaker and its regulator. The former is located at the …

Abstract Amyotrophic Lateral Sclerosis (ALS) disease severity is usually measured using the
subjective, questionnaire-based revised ALS Functional Rating Scale (ALSFRS-R) …

Physical activity (PA) is a complex human behavior, which implies that multiple dimensions
need to be taken into account in order to reveal a complete picture of the PA behavior profile …

Unconstrained human movement can be broken down into a series of stereotyped motifs or
'syllables' in an unsupervised fashion. Sequences of these syllables can be represented by …

Abstract Background People with PD (PWP) have an increased risk of becoming inactive.
Wearable sensors can provide insights into daily physical activity and walking patterns …

Current outcomes in neuromuscular disorder clinical trials include motor function scales,
timed tests, and strength measures performed by trained clinical evaluators. These …

Body-Worn Sensors (BWS) provide reliable objective and continuous assessment of
Parkinson's disease (PD) motor symptoms, but their implementation in clinical routine has …

Abstract Study Objectives We conducted a prospective study to quantify motor activity during
sleep measured by actigraphy before and after 3 months of treatment with clonazepam in …

The benefits of daily-living physical activity are clear. Nonetheless, the relationship between
physical activity levels and motor subtypes of Parkinson's disease (PD), ie, tremor dominant …