[HTML][HTML] Host Innate Immune Responses to Acinetobacter baumannii Infection

W Chen - Frontiers in Cellular and Infection Microbiology, 2020 - frontiersin.org
Acinetobacter baumannii has emerged as a major threat to global public health and is one
of the key human pathogens in healthcare (nosocomial and community-acquired) …

ROS/TXNIP pathway contributes to thrombin induced NLRP3 inflammasome activation and cell apoptosis in microglia

X Ye, D Zuo, L Yu, L Zhang, J Tang, C Cui… - Biochemical and …, 2017 - Elsevier
There is no effective therapy for intracerebral hemorrhage (ICH) because of poor
understanding of the mechanisms of brain injury after hemorrhage. The NLRP3 …

[HTML][HTML] Cathepsin L-containing exosomes from α-synuclein-activated microglia induce neurotoxicity through the P2X7 receptor

T Jiang, C Xu, S Gao, J Zhang, J Zheng, X Wu… - NPJ Parkinson's …, 2022 - nature.com
Uncontrolled microglial activation is pivotal to the pathogenesis of Parkinson's disease (PD),
which can secrete Cathepsin L (CTSL) to affect the survival of neurons in the PD patients; …

Type I IFN operates pyroptosis and necroptosis during multidrug-resistant A. baumannii infection

Y Li, X Guo, C Hu, Y Du, C Guo, D Wang… - Cell Death & …, 2018 - nature.com
Multidrug-resistant Acinetobacter baumannii, a common pathogen responsible for
nosocomial infections, is the main cause for outbreaks of infectious diseases, such as …

Inflammasome activation in acute lung injury

MJ McVey, BE Steinberg… - American Journal of …, 2021 - journals.physiology.org
Inflammasomes are multiprotein complexes tasked with sensing endogenous or exogenous
inflammatory signals and integrating this signal into a downstream response. Inflammasome …

[HTML][HTML] IL-1β production by intermediate monocytes is associated with immunopathology in cutaneous leishmaniasis

D Santos, TM Campos, M Saldanha, SC Oliveira… - Journal of Investigative …, 2018 - Elsevier
Cutaneous leishmaniasis due to Leishmania braziliensis infection is an inflammatory
disease in which skin ulcer development is associated with mononuclear cell infiltrate and …

[HTML][HTML] The intracellular life of Acinetobacter baumannii

A Maure, E Robino, C Van der Henst - Trends in Microbiology, 2023 - cell.com
Acinetobacter baumannii is a Gram-negative opportunistic bacterium responsible for
nosocomial and community-acquired infections. This pathogen is globally disseminated and …

[HTML][HTML] The potential role of inflammation in modulating endogenous hippocampal neurogenesis after spinal cord injury

A Sefiani, CG Geoffroy - Frontiers in Neuroscience, 2021 - frontiersin.org
Currently there are approximately 291,000 people suffering from a spinal cord injury (SCI) in
the United States. SCI is associated with traumatic changes in mobility and neuralgia, as …

[HTML][HTML] OmpA Protein-Deficient Acinetobacter baumannii Outer Membrane Vesicles Trigger Reduced Inflammatory Response

J Skerniškytė, E Karazijaitė, A Lučiūnaitė… - Pathogens, 2021 - mdpi.com
Multidrug resistant Acinetobacter baumannii shows a growing number of nosocomial
infections worldwide during the last decade. The outer membrane vesicles (OMVs) …

Interplay between peptidoglycan biology and virulence in Gram-negative pathogens

C Juan, G Torrens, IM Barceló… - … and Molecular Biology …, 2018 - Am Soc Microbiol
The clinical and epidemiological threat of the growing antimicrobial resistance in Gram-
negative pathogens, particularly for β-lactams, the most frequently used and relevant …