Design and Synthesis of l-1′-Homologated Adenosine Derivatives as Potential Anti-inflammatory Agents

M Nguyen, MA Aslam, Y Nguyen, HMA Javaid… - ACS …, 2023 - ACS Publications
Inflammatory responses are fundamental protective warning mechanisms. However, in
certain instances, they contribute significantly to the development of several chronic …

Mechanism and material basis of Lianhua Qingwen capsule for improving clinical cure rate of COVID-19: a study based on network pharmacology and molecular …

H Yan, C Zou - Nan Fang yi ke da xue xue bao= Journal of …, 2021 - europepmc.org
Objective To explore the potential targets, signal pathways and biological functions that
mediate the effect of Lianhua Qingwen capsule in improving clinical cure rate of COVID-19 …

[HTML][HTML] Microbial characterization of the nasal cavity in patients with allergic rhinitis and non-allergic rhinitis

Y Che, N Wang, Q Ma, J Liu, Z Xu, Q Li… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction Although recent studies have shown that the human microbiome is involved in
the pathogenesis of allergic diseases, the impact of microbiota on allergic rhinitis (AR) and …

[HTML][HTML] Acinetobacter baumannii outer membrane protein 34 elicits NLRP3 inflammasome activation via mitochondria-derived reactive oxygen species in RAW264. 7 …

Z An, J Su - Microbes and Infection, 2019 - Elsevier
Acinetobacter baumannii (A. baumannii) is a Gram-negative bacterium, which acts as an
opportunistic pathogen and causes hospital-acquired pneumonia and bacteremia by …

High-sensitivity C-reactive protein, low-grade systemic inflammation and type 2 diabetes mellitus: a two-sample Mendelian randomization study

R Noordam, CH Oudt, MM Bos, RAJ Smit… - Nutrition, Metabolism …, 2018 - Elsevier
Background and aims The role of inflammation in type 2 diabetes mellitus (T2D) remains
unclear. We investigated the associations of high sensitivity C-reactive protein (hsCRP) …

[HTML][HTML] Topical Administration of Heat-Killed Enterococcus faecalis Strain KH2 Promotes Re-Epithelialization and Granulation Tissue Formation during Skin Wound …

H Tanno, E Kanno, S Kurosaka, Y Oikawa, T Watanabe… - Biomedicines, 2021 - mdpi.com
Lactic acid bacteria (LAB) are known to have beneficial effects on immune responses when
they are orally administered as bacterial products. Although the beneficial effects of LAB …

[HTML][HTML] Analysis of immune responses in Acinetobacter baumannii-infected klotho knockout mice: a mouse model of Acinetobacter baumannii infection in aged hosts

Y Sato, S Tansho-Nagakawa, T Ubagai… - Frontiers in …, 2020 - frontiersin.org
Acinetobacter baumannii is an important opportunistic pathogen that primarily afflicts elderly
people. To clarify the pathogenicity of A. baumannii in the elderly, we investigated immune …

[HTML][HTML] Differential activation of NLRP3 inflammasome by Acinetobacter baumannii strains

FJ Li, L Starrs, A Mathur, H Ishii, SM Man, G Burgio - Plos one, 2022 - journals.plos.org
Acinetobacter baumannii is an emerging nosocomial, opportunistic pathogen with growing
clinical significance globally. A. baumannii has an exceptional ability to rapidly develop drug …

[HTML][HTML] Antimicrobial, Immunomodulatory and Anti-Inflammatory Potential of Liposomal Thymoquinone: Implications in the Treatment of Bacterial Pneumonia in …

KS Allemailem, A Almatroudi, F Alrumaihi… - Biomedicines, 2021 - mdpi.com
Acinetobacter baumannii has recently been increasing as an aggressive pathogen in
immunocompromised persons. In the present study, we determined the in vitro antibacterial …

Outer membrane protein A inhibits the degradation of caspase-1 to regulate NLRP3 inflammasome activation and exacerbate the Acinetobacter baumannii pulmonary …

Y Li, C Peng, D Zhao, L Liu, B Guo, M Shi, Y Xiao… - Microbial …, 2021 - Elsevier
Abstract Acinetobacter baumannii (A. baumannii), one of the major pathogens that causes
severe nosocomial infections, is characterised by a high prevalence of drug resistance. It …