Cytokines are critical mediators that oversee and regulate immune and inflammatory
responses via complex networks and serve as biomarkers for many diseases. Quantification …

ABSTRACT Introduction: Transforming Growth Factor-Beta (TGF-β) is a master regulator of
numerous cellular functions including cellular immunity. In cancer, TGF-β can function as a …

Radiation-induced endothelial/vascular injury is a major complicating factor in radiotherapy
and a leading cause of morbidity and mortality in nuclear or radiological catastrophes …

The COVID-19 pandemic has caused a global health crisis, with no specific antiviral to treat
the infection and the absence of a suitable vaccine to prevent it. While some individuals …

Depression onset peaks during adolescence and young adulthood. Current treatments are
only moderately effective, driving the search for novel pathophysiological mechanisms …

Alzheimer's disease (AD) is the most prevalent neurodegenerative disease commonly
diagnosed among the elderly population. AD is characterized by the loss of synaptic …

The immune system is one of the main defence mechanisms of the human body.
Inadequacy of this system or immunodeficiency results in increased risk of infections and …

Mesenchymal stromal cells (MSCs) are characterized by a regulatory phenotype and
respond promptly to the environmental signals modulating their secretory activity. An …

Objectives To examine the effect of aerobic and resistant exercise intervention on
inflammaging in middle-aged and older adults with type 2 diabetes mellitus (T2DM) using …

Histone acetyltransferases (HATs) and histone deacetylases (HDACs) counteract with each
other to regulate gene expression by altering chromatin structure. Aberrant HDAC activity …