Adenocarcinoma: a unique cervical cancer

LT Gien, MC Beauchemin, G Thomas - Gynecologic oncology, 2010 - Elsevier
Adenocarcinoma of the cervix constitutes only approximately 20% of all cervical carcinomas;
therefore, specific Level 1 evidence to guide patient management is lacking. Most trials have …

Kinases as targets in the treatment of solid tumors

G Giamas, YL Man, H Hirner, J Bischof, K Kramer… - Cellular signalling, 2010 - Elsevier
The protein kinase family, one of the largest gene families in eukaryotes, plays an important
role in regulating various cellular processes such as cell proliferation, cell death, cell cycle …

In vivo antitumor effect of an intracellular single‐chain antibody fragment against the E7 oncoprotein of human papillomavirus 16

L Accardi, F Paolini, A Mandarino… - … journal of cancer, 2014 - Wiley Online Library
Human papillomavirus (HPV)‐associated tumors still represent an urgent problem of public
health in spite of the efficacy of the prophylactic HPV vaccines. Specific antibodies in single …

[HTML][HTML] Treatment options in recurrent cervical cancer

A Gadducci, R Tana, S Cosio… - Oncology …, 2010 - spandidos-publications.com
The management of recurrent cervical cancer depends mainly on previous treatment and on
the site and extent of recurrence. Concurrent cisplatin-based chemo-radiation is the …

Prognostic cell biological markers in cervical cancer patients primarily treated with (chemo) radiation: a systematic review

MG Noordhuis, JJH Eijsink, F Roossink… - International Journal of …, 2011 - Elsevier
The aim of this study was to systematically review the prognostic and predictive significance
of cell biological markers in cervical cancer patients primarily treated with (chemo) radiation …

Anti‐glypican‐1 antibody‐drug conjugate exhibits potent preclinical antitumor activity against glypican‐1 positive uterine cervical cancer

S Matsuzaki, S Serada, K Hiramatsu… - … journal of cancer, 2018 - Wiley Online Library
Glypican‐1 (GPC1) is highly expressed in solid tumors, especially squamous cell
carcinomas (SCCs), and is thought to be associated with disease progression. We explored …

[HTML][HTML] Sphingosine kinase 1 is a reliable prognostic factor and a novel therapeutic target for uterine cervical cancer

HS Kim, G Yoon, JY Ryu, YJ Cho, JJ Choi, YY Lee… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Abstract Sphingosine kinase 1 (SPHK1), an oncogenic kinase, has previously been found to
be upregulated in various types of human malignancy and to play a crucial role in tumor …

miR-454-3p promotes proliferation and induces apoptosis in human cervical cancer cells by targeting TRIM3

Y Song, Q Guo, S Gao, K Hua - Biochemical and Biophysical Research …, 2019 - Elsevier
Abnormally expressed microRNAs have been demonstrated related to the development and
progression of cervical cancer. However, the molecular mechanisms remain largely unkown …

Anti-angiogenesis agents in metastatic or recurrent cervical cancer

BJ Monk, LJ Willmott, DA Sumner - Gynecologic oncology, 2010 - Elsevier
While the incidence of cervical cancer has declined significantly in the United States, it still
remains a serious American health threat. When detected early, cervical cancer is generally …

[HTML][HTML] Emerging biological treatments for uterine cervical carcinoma

P Vici, L Mariani, L Pizzuti, D Sergi, L Di Lauro… - Journal of …, 2014 - ncbi.nlm.nih.gov
Cervical cancer is the third most common cancer worldwide, and the development of new
diagnosis, prognostic, and treatment strategies is a major interest for public health. Cisplatin …