Genetic organization of polytene chromosomes

IF Zhimulëv - Advances in genetics, 1999 - Elsevier
Publisher Summary The interphase polytene chromosome is morphologically differentiated
into tightly compacted (the chromomeric) and decompacted (the interchomomeric) regions …

Compartmentalization of RNA processing factors within nuclear speckles

PJ Mintz, DL Spector - Journal of structural biology, 2000 - Elsevier
In the mammalian cell nucleus pre-mRNA splicing factors are organized in a speckled
pattern. The fluorescence signal within speckles appears homogeneous when cells are …

Pre‐mRNA splicing during transcription in the mammalian system

A Pandya‐Jones - Wiley Interdisciplinary Reviews: RNA, 2011 - Wiley Online Library
Splicing of RNA polymerase II transcripts is a crucial step in gene expression and a key
generator of mRNA diversity. Splicing and transcription have generally been studied in …

HEL/UAP56 binds cotranscriptionally to the Balbiani ring pre-mRNA in an intron-independent manner and accompanies the BR mRNP to the nuclear pore

E Kiesler, F Miralles, N Visa - Current Biology, 2002 - cell.com
The splicing factor UAP56/HEL/Sub2p is essential for mRNA export [1-4]. It has been
proposed [1, 2] that UAP56/HEL/Sub2p interacts with the pre-mRNA during splicing and …

The influence of Argonaute proteins on alternative RNA splicing

E Batsché, M Ameyar‐Zazoua - Wiley Interdisciplinary Reviews …, 2015 - Wiley Online Library
Alternative splicing of precursor RNAs is an important process in multicellular species
because it impacts several aspects of gene expression: from the increase of protein …

A protein of the SR family of splicing factors binds extensively to exonic Balbiani ring pre-mRNA and accompanies the RNA from the gene to the nuclear pore.

AT Alzhanova-Ericsson, X Sun, N Visa… - Genes & …, 1996 - genesdev.cshlp.org
We report on the molecular cloning and intracellular localization of a heterogeneous nuclear
ribonucleoprotein (hnRNP), Ct-hrp45, one of the major components of pre-mRNP particles …

The Balbiani ring story: synthesis, assembly, processing, and transport of specific messenger RNA–protein complexes

P Björk, L Wieslander - Annual Review Of Biochemistry, 2015 - annualreviews.org
Eukaryotic gene expression is the result of the integrated action of multimolecular
machineries. These machineries associate with gene transcripts, often already nascent …

Dynamic organization of pre‐mRNA splicing factors

S Huang, DL Spector - Journal of cellular biochemistry, 1996 - Wiley Online Library
Studies from several laboratories during the past few years have increased our
understanding towards the dynamic organization of pre‐mRNA splicing factors in the …

Proteins C1 and C2 of heterogeneous nuclear ribonucleoprotein complexes bind RNA in a highly cooperative fashion: support for their contiguous deposition on pre …

JG McAfee, SR Soltaninassab, ME Lindsay… - Biochemistry, 1996 - ACS Publications
Proteins C1 and C2 together comprise about one-third the protein mass of mammalian core
40S heterogeneous nuclear ribonucleoprotein particles (40S hnRNP) and exist as …

Identification of two RNA-binding proteins in Balbiani ring premessenger ribonucleoprotein granules and presence of these proteins in specific subsets of …

T Wurtz, E Kiseleva, G Nacheva… - … and cellular biology, 1996 - Am Soc Microbiol
Balbiani ring (BR) granules are premessenger ribonucleoprotein particles (RNPs)
generated in giant chromosomal puffs, the BRs, in the larval salivary glands of the dipteran …