[PDF][PDF] Beyond epithelial damage: vascular and endothelial contributions to idiopathic pulmonary fibrosis

J May, JA Mitchell, RG Jenkins - Journal of Clinical …, 2023 - Am Soc Clin Investig
Idiopathic pulmonary fibrosis (IPF) is a progressive scarring disease of the lung with poor
survival. The incidence and mortality of IPF are rising, but treatment remains limited …

Pulmonary Hypertension in the Course of Interstitial Lung Diseases—A Personalised Approach Is Needed to Identify a Dominant Cause and Provide an Effective …

A Kacprzak, W Tomkowski, M Szturmowicz - Diagnostics, 2023 - mdpi.com
The prevalence of pulmonary hypertension (PH) complicating interstitial lung diseases
(ILDs) is 3.5–15% at an early stage, and up to 90% in ILD patients listed for lung …

Elucidating shared biomarkers in gastroesophageal reflux disease and idiopathic pulmonary fibrosis: insights into novel therapeutic targets and the role of angelicae …

X Wu, X Xiao, H Fang, C He, H Wang… - Frontiers in …, 2024 - frontiersin.org
Background: The etiological underpinnings of gastroesophageal reflux disease (GERD) and
idiopathic pulmonary fibrosis (IPF) remain elusive, coupled with a scarcity of effective …

What is new in the treatment of interstitial lung diseases.

V Sotiropoulou, T Karampitsakos, M Katsaras… - …, 2023 - search.ebscohost.com
Interstitial lung diseases (ILDs) comprise an heterogenous group of more than 200
pulmonary disorders characterized by lung architectural distortion, with variable amount of …

Phosphodiesterase inhibitors and lung diseases

I Stolfa, C Page - Advances in Pharmacology, 2023 - Elsevier
Phosphodiesterase enzymes (PDE) have long been known as regulators of cAMP and
cGMP, second messengers involved in various signaling pathways and expressed in a …

[图书][B] Anti-Fibrotic Effects of the Secretome of Human Adipose-Derived Mesenchymal Stromal Cells: in Vitro Studies

M Brizio - 2023 - search.proquest.com
Background: Fibrotic diseases represent an increasing cause of morbidity, mortality, and
financial burden worldwide. Fibrosis is a pathological wound healing response …

[图书][B] Mouse models of systemic sclerosis-interstitial lung disease: hypochlorous acid (HOCl)-induced or bleomycin delivered by osmotic minipump?

A Morozan - 2022 - search.proquest.com
Background: Systemic sclerosis (SSc; scleroderma) is an autoimmune disease
characterized by excessive collagen synthesis by fibroblasts, vascular abnormalities, and …