Current research on inositols mainly focuses on myo-inositol (Ins) derivatives in eukaryotic
cells, and in particular on the many roles of Ins phospholipids and polyphosphorylated Ins …

Abstract Inositol 1, 4, 5‐trisphosphate (IP3) is a second messenger that induces the release
of Ca2+ from the endoplasmic reticulum (ER). The IP3 receptor (IP3R) was discovered as a …

It is clear from the preceding overview of histamine receptor pharmacology that research into
the pharmacology of histamine receptors is at an exciting stage of development. The rapid …

Severe norpA mutations in Drosophila eliminate the photoreceptor potential and render the
fly completely blind. Recent biochemical analyses have shown that norpA mutants lack …

There is evidence that the polymerization of actin takes place at the plasma membrane1,
and that profilactin (profilin/actin complex), the unpolymerized form of actin found in extracts …

Alterations in the level of dietary inositol can significantly influence the concentration of free
inositol and inositol-containing phospholipid in the circulation and in selected mammalian …

Formation of the transparent ocular lens of vertebrates mirrors many general features of
normal development. The presumptive lens ectoderm is induced to differentiate into a lens …

Ca2+-activated, phospholipid-dependent protein kinase from various mammalian tissues
(Takai, Y., Kishimoto, A., Iwasa, Y., Kawahara, Y., Mori, T., and Nishizuka, Y (1979) J. Biol …

Inositol 1, 4, 5-trisphosphate receptors (IP3R) and their relatives, ryanodine receptors, are
the channels that most often mediate Ca2+ release from intracellular stores. Their regulation …

Several studies have shown impairement of endothelium-dependent relaxations as well as
increased release of vasoconstrictor prostanoids in arteries from diabetic animals and …