The physiological effects of many extracellular neurotransmitters, hormones, growth factors,
and other stimuli are mediated by receptor-promoted activation of phospholipase C (PLC) …

✓ Recent developments in the field of cerebral circulation and metabolism are reviewed,
with emphasis on circulatory and metabolic events that have a bearing on brain damage …

Calcium signaling is a process whereby the extremely low cytoplasmic Ca2+ concentration
increases in a deliberate and specific manner to trigger downstream cellular events. Virtually …

Definitions: Arachidonic acid is 5, 8, 11, 14-icosatetraenoic acid. Eicosanoid is the term
introduced by Corey et al.(1980) to cover all products of arachidonate metabolism, whether …

The formation of inositol phosphates in response to agonists was studied in brain slices,
parotid gland fragments and in the insect salivary gland. The tissues were first incubated …

Transmembrane signals initiated by a broad range of extracellular stimuli converge on
nodes that regulate phospholipase C (PLC)–dependent inositol lipid hydrolysis for signal …

Ca2+-mobilizing agonists, including hormones, neurotrans-mitters and growth factors, cause
profound changes in cellular lipid metabolism. These changes are initiated by receptor …

Rapid to moderately rapid changes in intracellular Ca2+ concentration, or Ca2+ signals,
control a variety of critical cellular functions in the immune system. These signals are …

In the almost 70 years since the first hints of its existence, the phosphoinositide,
phosphatidyl-D-myo-inositol 4, 5-bisphosphate has been found to be central in the …

The effects of catecholamines in the central and peripheral nervous systems appear to be
mediated through interactions with 2 major classes of receptor: α-adrenoceptors and β …