Cysteine and homocysteine as biomarker of various diseases

T Rehman, MA Shabbir… - Food science & …, 2020 - Wiley Online Library
Cysteine and homocysteine (Hcy), both sulfur‐containing amino acids (AAs), produced from
methionine another sulfur‐containing amino acid, which is converted to Hcy and further …

[HTML][HTML] The contribution of homocysteine metabolism disruption to endothelial dysfunction: state-of-the-art

R Esse, M Barroso, I Tavares de Almeida… - International journal of …, 2019 - mdpi.com
Homocysteine (Hcy) is a sulfur-containing non-proteinogenic amino acid formed during the
metabolism of the essential amino acid methionine. Hcy is considered a risk factor for …

[HTML][HTML] Date Palm Fruit (Phoenix dactylifera): Effects on Vascular Health and Future Research Directions

YA Al-Dashti, RR Holt, CL Keen… - International journal of …, 2021 - mdpi.com
Cardiovascular disease is a leading cause of death globally, presenting an immense public
and economic burden. Studies on cardioprotective foods and their bioactive components are …

[HTML][HTML] Impaired folate-mediated one-carbon metabolism in type 2 diabetes, late-onset Alzheimer's disease and long COVID

MR Hayden, SC Tyagi - Medicina, 2021 - mdpi.com
Impaired folate-mediated one-carbon metabolism (FOCM) is associated with many
pathologies and developmental abnormalities. FOCM is a metabolic network of …

[HTML][HTML] Recent updates and advances in Winiwarter-Buerger disease (thromboangiitis obliterans): biomolecular mechanisms, diagnostics and clinical consequences

B Fazeli, D Ligi, S Keramat, R Maniscalco… - Diagnostics, 2021 - mdpi.com
Thromboangiitis obliterans (TAO) or Buerger's disease is a segmental inflammatory,
thrombotic occlusive peripheral vascular disease with unknown aetiology that usually …

[HTML][HTML] Integration of metabolomics and proteomics in exploring the endothelial dysfunction mechanism induced by serum exosomes from diabetic retinopathy and …

J Yang, D Liu, Z Liu - Frontiers in endocrinology, 2022 - frontiersin.org
Background The prevalence of diabetic microvascular diseases has increased significantly
worldwide, the most common of which are diabetic nephropathy (DN) and diabetic …

[HTML][HTML] Hypothesis: neuroglia activation due to increased peripheral and CNS proinflammatory cytokines/chemokines with neuroinflammation may result in long …

MR Hayden - Neuroglia, 2021 - mdpi.com
The COVID-19 pandemic has paralleled the great Spanish flu pandemic of 1918–1919 in
the United States. Previous historical accounts have strongly suggested a post-viral …

The cardioprotective effects of hydrogen sulfide by targeting endoplasmic reticulum stress and the Nrf2 signaling pathway: a review

F Yarmohammadi, AW Hayes, G Karimi - BioFactors, 2021 - Wiley Online Library
Cardiac diseases are emerging due to lifestyle, urbanization, and the accelerated aging
process. Oxidative stress has been associated with cardiac injury progression through …

Evidence for TET-mediated DNA demethylation as an epigenetic alteration in cumulus granulosa cells of women with polycystic ovary syndrome

P Sagvekar, G Shinde, V Mangoli… - Molecular Human …, 2022 - academic.oup.com
Peripheral and tissue-specific alterations in global DNA methylation (5-methylcytosine
(5mC)) and DNA hydroxymethylation (5-hydroxymethylcytosine (5hmC)) profiles have been …

[HTML][HTML] Diet-Induced Severe Hyperhomocysteinemia Promotes Atherosclerosis Progression and Dysregulates the Plasma Metabolome in Apolipoprotein-E-Deficient …

SG Andrews, AM Koehle, D Paudel, T Neuberger… - Nutrients, 2024 - mdpi.com
Atherosclerosis and resulting cardiovascular disease are the leading causes of death in the
US. Hyperhomocysteinemia (HHcy), or the accumulation of the intermediate amino acid …