Mesenchymal stem cell migration and tissue repair

X Fu, G Liu, A Halim, Y Ju, Q Luo, G Song - Cells, 2019 - mdpi.com
Mesenchymal stem cells (MSCs) are multilineage cells with the ability to self-renew and
differentiate into a variety of cell types, which play key roles in tissue healing and …

Common mechanisms underlying diabetic vascular complications: focus on the interaction of metabolic disorders, immuno-inflammation, and endothelial dysfunction

C Xue, K Chen, Z Gao, T Bao, LS Dong, L Zhao… - Cell Communication and …, 2023 - Springer
Diabetic vascular complications (DVCs), including macro-and micro-angiopathy, account for
a high percentage of mortality in patients with diabetes mellitus (DM). Endothelial …

Human umbilical cord-derived mesenchymal stem cells not only ameliorate blood glucose but also protect vascular endothelium from diabetic damage through a …

Y Liu, J Chen, H Liang, Y Cai, X Li, L Yan… - Stem cell research & …, 2022 - Springer
Background Endothelial damage is an initial step of macro-and micro-vasculature
dysfunctions in diabetic patients, accounting for a high incidence of diabetic vascular …

Down-regulation of WWP2 aggravates Type 2 diabetes mellitus-induced vascular endothelial injury through modulating ubiquitination and degradation of DDX3X

S You, J Xu, Z Yin, B Wu, P Wang, M Hao… - Cardiovascular …, 2023 - Springer
Background Endothelial injury caused by Type 2 diabetes mellitus (T2DM) is considered as
a mainstay in the pathophysiology of diabetic vascular complications (DVCs). However, the …

Neovascularization: the main mechanism of MSCs in ischemic heart disease therapy

W Shi, Q Xin, R Yuan, Y Yuan, W Cong… - Frontiers in …, 2021 - frontiersin.org
Mesenchymal stem cell (MSC) transplantation after myocardial infarction (MI) has been
shown to effectively limit the infarct area in numerous clinical and preclinical studies …

Cardiovascular protection with a long-acting GLP-1 receptor agonist liraglutide: an experimental update

C Vandemark, J Nguyen, ZQ Zhao - Molecules, 2023 - mdpi.com
Angiotensin II (Ang II), a peptide hormone generated as part of the renin–angiotensin
system, has been implicated in the pathophysiology of many cardiovascular diseases such …

Glucagon-like peptide-1 analog liraglutide attenuates pressure-overload induced cardiac hypertrophy and apoptosis through activating ATP sensitive potassium …

XJ Bai, JT Hao, RH Zheng, CP Yan, J Wang… - … drugs and therapy, 2021 - Springer
Purpose This study aimed to investigate whether inhibition of glucagon-like peptide-1 (GLP-
1) on pressure overload induced cardiac hypertrophy and apoptosis is related to activation …

Mesenchymal stem cells and exosomes improve cognitive function in the aging brain by promoting neurogenesis

X Zhang, X Hou, L Te, Z Zhongsheng… - Frontiers in aging …, 2022 - frontiersin.org
Biologically speaking, normal aging is a spontaneous and inevitable process of organisms
over time. It is a complex natural phenomenon that manifests itself in the form of …

Clopidogrel-induced gastric injury in rats is attenuated by stable gastric pentadecapeptide BPC 157

H Wu, M Wei, N Li, Q Lu, SM Shrestha… - Drug Design …, 2020 - Taylor & Francis
Aim Although Clopidogrel is safe in healthy volunteers, it can induce recurrence of gastric
ulcers in high-risk patients. Here, we investigated the protective effect of the natural product …

Behavior of smooth muscle cells under hypoxic conditions: possible implications on the varicose vein endothelium

MA Ortega, B Romero, Á Asúnsolo… - BioMed Research …, 2018 - Wiley Online Library
Varicose veins are a disease with high incidence and prevalence. In the venous wall, the
smooth muscle cells (SMCs) act in the vascular homeostasis that secretes multiple …