The use of patient-derived dendritic cells (DCs) as a means to elicit therapeutically relevant
immune responses in cancer patients has been extensively investigated throughout the past …

An increasing number of studies is focusing on the role of myeloid-derived suppressor cells
(MDSCs) in the suppression of antitumor immune responses. Although the main site of …

Simple Summary A common characteristic of multiple myeloma (MM) is the dysfunction of
patients' immune system, a condition termed immunosuppression. This state is mainly due to …

Our evolving understandings of cell-material interactions provide insights for using polymers
to modulate cell behaviour that may lead to therapeutic applications. It is known that in …

Abstract Background Gansui-Banxia Decoction (GSBXD) is a classic formula of traditional
Chinese medical (TCM) sage Zhang Zhongjing to treat stagnation of evil heat and …

Gastrointestinal (GI) cancer encompasses a range of malignancies that originate in the
digestive system, which together represent the most common form of cancer diagnosed …

Cisplatin and other platinum-based drugs are used frequently for treatment of lung cancer.
However, their clinical performance are usually limited by drug resistance or toxic effects …

The bone marrow provides a protected environment for generating a vast array of cell types.
Bones are thus a dynamic source of structural components and soluble factors used either …

Immune evasion is a recently defined hallmark of cancer, and immunotherapeutic
approaches that stimulate an immune response to tumours are gaining recognition …

During the past two decades, it has become increasingly clear that the antineoplastic effects
of radiation therapy do not simply reflect the ability of X-, β-and γ-rays to damage …