The role of helper T cells in psoriasis
P Hu, M Wang, H Gao, A Zheng, J Li, D Mu… - Frontiers in …, 2021 - frontiersin.org
Psoriasis is a complex, chronic relapsing and inflammatory skin disorder with a prevalence
of approximately 2% in the general population worldwide. Psoriasis can be triggered by …
of approximately 2% in the general population worldwide. Psoriasis can be triggered by …
Disease modification in inflammatory skin disorders: opportunities and challenges
T Bieber - Nature Reviews Drug Discovery, 2023 - nature.com
Progress in understanding of the mechanisms underlying chronic inflammatory skin
disorders, such as atopic dermatitis and psoriasis vulgaris, has led to new treatment options …
disorders, such as atopic dermatitis and psoriasis vulgaris, has led to new treatment options …
Single-atom catalysts-based catalytic ROS clearance for efficient psoriasis treatment and relapse prevention via restoring ESR1
X Lu, L Kuai, F Huang, J Jiang, J Song, Y Liu… - Nature …, 2023 - nature.com
Psoriasis is a common inflammatory disease of especially high recurrence rate (90%) which
is suffered by approximately 3% of the world population. The overexpression of reactive …
is suffered by approximately 3% of the world population. The overexpression of reactive …
Unmet medical needs in chronic, non-communicable inflammatory skin diseases
H Ujiie, D Rosmarin, MP Schön, S Ständer… - Frontiers in …, 2022 - frontiersin.org
An estimated 20–25% of the population is affected by chronic, non-communicable
inflammatory skin diseases. Chronic skin inflammation has many causes. Among the most …
inflammatory skin diseases. Chronic skin inflammation has many causes. Among the most …
[HTML][HTML] Exploring the links between obesity and psoriasis: a comprehensive review
G Barros, P Duran, I Vera, V Bermúdez - International Journal of …, 2022 - mdpi.com
Obesity is a major public health issue worldwide since it is associated with the development
of chronic comorbidities such as type 2 diabetes, dyslipidemias, atherosclerosis, some …
of chronic comorbidities such as type 2 diabetes, dyslipidemias, atherosclerosis, some …
Signaling pathways and targeted therapies for psoriasis
J Guo, H Zhang, W Lin, L Lu, J Su… - Signal Transduction and …, 2023 - nature.com
Psoriasis is a common, chronic, and inflammatory skin disease with a high burden on
individuals, health systems, and society worldwide. With the immunological pathologies and …
individuals, health systems, and society worldwide. With the immunological pathologies and …
Plant exosomes fused with engineered mesenchymal stem cell‐derived nanovesicles for synergistic therapy of autoimmune skin disorders
R Huang, B Jia, D Su, M Li, Z Xu, C He… - Journal of …, 2023 - Wiley Online Library
Existing therapeutics for autoimmune diseases remain problematic due to low efficacy,
severe side effects, and difficulties to reach target tissues. Herein, we design multifunctional …
severe side effects, and difficulties to reach target tissues. Herein, we design multifunctional …
Inflammation and psoriasis: a comprehensive review
AM Man, MS Orăsan, OA Hoteiuc… - International Journal of …, 2023 - mdpi.com
Psoriasis is an immune-mediated disease with a strong genetic component that brings many
challenges to sick individuals, such as chronic illness, and which has multiple associated …
challenges to sick individuals, such as chronic illness, and which has multiple associated …
Long-term efficacy and safety of risankizumab for moderate to severe psoriasis: a 2-year real-life retrospective study
M Megna, A Ruggiero, T Battista, L Marano… - Journal of Clinical …, 2023 - mdpi.com
Risankizumab is a humanized IgG monoclonal antibody inhibitor of IL23 and has been
recently approved by the EMA and the FDA for the treatment of moderate to severe plaque …
recently approved by the EMA and the FDA for the treatment of moderate to severe plaque …
Organizing structural principles of the IL-17 ligand–receptor axis
The IL-17 family of cytokines and receptors have central roles in host defence against
infection and development of inflammatory diseases. The compositions and structures of …
infection and development of inflammatory diseases. The compositions and structures of …