Developmental and epileptic encephalopathies (DEEs) are a heterogeneous group of
disorders characterized by early-onset, often severe epileptic seizures and EEG …

Insulin and insulin-like growth factor 1 (IGF1) signalling play a central role in the
development and maintenance of neurons in the brain, and in humans neurodevelopmental …

Neuropsychiatric disorders affect a large proportion of the global population and there is an
urgent need to understand the pathogenesis and to develop novel and improved treatments …

Epilepsy is a chronic brain disease and, considering the amount of people affected of all
ages worldwide, one of the most common neurological disorders. Over 20 novel antiseizure …

The CRISPR‐Cas9 technology has the potential to revolutionize the treatment of various
diseases, including Rett syndrome, by enabling the correction of genes or mutations in …

Alzheimer's disease (AD) is a chronic illness marked by increasing cognitive decline and
nervous system deterioration. At this time, there is no known medication that will stop the …

Approval of therapeutic RNA molecules, including RNA vaccines, has paved the way for
next-generation treatment strategies for various diseases. Oligonucleotide-based …

Induced pluripotent stem cells (iPS cells) represent a particularly versatile stem cell type for
a large array of applications in biology and medicine. Taking full advantage of iPS cell …

Human organoids are small, self-organized, three-dimensional (3D) tissue cultures that
have started to revolutionize medical science in terms of understanding disease, testing …

Following the increase in life expectancy, the prevalence of Parkinson's disease (PD) as the
most common movement disorder is expected to rise. Despite the incredibly huge efforts in …