Atherosclerosis is an inflammatory disease. Because high plasma concentrations of
cholesterol, in particular those of low-density lipoprotein (LDL) cholesterol, are one of the …

Metabolism, like other aspects of life, involves tradeoffs. Oxidant by-products of normal
metabolism cause extensive damage to DNA, protein, and lipid. We argue that this damage …

Background: Studies of whole grain and chronic disease have often included bran-enriched
foods and other ingredients that do not meet the current definition of whole grains …

Free radical production occurs continuously in all cells as part of normal cellular function.
However, excess free radical production originating from endogenous or exogenous …

Background—The Lyon Diet Heart Study is a randomized secondary prevention trial aimed
at testing whether a Mediterranean-type diet may reduce the rate of recurrence after a first …

Healthy lifestyle and diet are associated with significant reduction in risk of obesity, type 2
diabetes, and cardiovascular diseases. Oxidative stress and the imbalance between …

Background The effects of dietary soluble fibers on blood cholesterol are uncertain.
Objective This meta-analysis of 67 controlled trials was performed to quantify the cholesterol …

Vitamin C is a powerful dietary antioxidant that has received considerable attention in the
literature related to its possible role in heart health. Although classical vitamin C deficiency …

Observational studies have suggested that the intake of flavonoids is associated with a
decreased risk of CVD. However, the results of these studies remain controversial. The aim …

This review focuses on the role of oxidative processes in atherosclerosis and its resultant
cardiovascular events. There is now a consensus that atherosclerosis represents a state of …