The surface of cells is coated with a dense layer of glycans, known as the cell glycocalyx.
The complex glycans in the glycocalyx are involved in various biological events, such as …

Mycobacterium tuberculosis (Mtb) modulates diverse cell death pathways to escape the host
immune responses and favor its dissemination, a complex process of interest in …

Great efforts have been directed toward alkene π bond amination. In contrast, analogous
functionalization of the adjacent C (sp3)–C (sp2) σ bonds is much rarer. Here we report how …

The cell walls of pathogenic and acidophilic bacteria, such as Mycobacterium tuberculosis
and Mycobacterium leprae, contain lipoarabinomannan and arabinogalactan. These …

Nitrogen metabolism is an important physiological process that affects the survival and
virulence of Mycobacterium tuberculosis. M. tuberculosis's utilization of nitrogen in the …

The co-occurrence of human immunodeficiency virus (HIV) and tuberculosis (TB) infection
poses a significant global health challenge. Treatment of HIV and TB co-infection often …

Glycoconjugates are the dominant components of the Mycobacterium tuberculosis cell wall.
These glycoconjugates are essential for the viability of Mtb and attribute to drug resistance …

Bilayers of mycolic acids (MAs) form the outer membrane of Mycobacterium tuberculosis that
has high strength and extremely low permeability for external molecules (including …

Arabinogalactan (AG) is an essential cell wall component in mycobacterial species,
including the deadly human pathogen Mycobacterium tuberculosis. It plays a pivotal role in …

There is a dearth of tuberculosis (TB) drug development activity as current therapeutic
treatments are inadequate due to the appearance of drug-resistant TB. The enzyme UDP …