Lung cancer has consistently ranked first as the cause of cancer-associated mortality. The 5-
year survival rate has risen slowly, and the main obstacle to improving the prognosis of …

Immunotherapy, including immunostimulation and immunosuppression, has seen significant
development in the last 10 years. Immunostimulation has been verified as effective in anti …

Exosome, a subpopulation of extracellular vesicles, plays diverse roles in various biological
processes. As one of the most abundant components of exosomes, exosomal proteins have …

In the era of multi-omic sciences, dogma on singular cause-effect in physio-pathological
processes is overcome and system biology approaches have been providing new …

Around the world, lung cancer has long been the main factor in cancer-related deaths, with
small-cell lung cancer (SCLC) being the deadliest form of lung cancer. Cancer cell-derived …

Small cell lung cancer (SCLC) elicits the generation of autoantibodies that result in unique
paraneoplastic neurological syndromes. The mechanistic basis for the formation of such …

Simple Summary Lung cancer is the biggest killer among cancers. Its mortality is related to
delayed diagnosis which is often achieved in the advanced stages of the disease when …

After years of disappointing clinical results, the tide has finally changed and complement
targeted-therapies have become a validated and accepted treatment option for several …

Complement is an ancient and complex network of the immune system and, as such, it plays
vital physiological roles, but it is also involved in numerous pathological processes. The …

Lung cancer is responsible for the most cancer-related mortality worldwide and the
mechanism of its development is poorly understood. Proteomics has become a powerful tool …