Pyroptosis is a novel regulated cell death (RCD) mode associated with inflammation and
innate immunity. Gasdermin E (GSDME), a crucial component of the gasdermin (GSDM) …

Macrophages are exceptionally diversified cell types and perform unique features and
functions when exposed to different stimuli within the specific microenvironment of various …

Background With the increasing prevalence of hypertension, diabetes, and obesity, the
incidence of kidney diseases is also increasing, resulting in a serious public burden …

Diclofenac (DF)-induced acute kidney injury (AKI) is characterized by glomerular dysfunction
and acute tubular necrosis. Due to limited treatment approaches, effective and safe drug …

Acute lung injury is a serious complication of sepsis with high morbidity and mortality.
Pyroptosis is a proinflammatory form of programmed cell death that leads to immune …

Idiopathic pulmonary fibrosis (IPF) is the severe form of interstitial pneumonias. Acute
exacerbation (AE) of IPF is characterized by progressive lung fibrosis with the irreversible …

Ferroptosis is an emerging and novel type of iron-dependent programmed cell death which
is mainly caused by the excessive deposition of free intracellular iron in the brain cells. This …

Sunitinib (SUN) is a chemotherapeutic agent clinically approved for treatment of metastatic
renal carcinoma. Despite its remarkable benefits, various renal toxicities have been reported …

Background Osteomyelitis is a refractory bone infectious disease, which usually results in
progressive bone destruction and bone loss. The invasion of pathogens and subsequent …

Globally, atherosclerosis a persistent inflammatory condition of the artery walls continues to
be the primary cause of cardiovascular illness and death. The ncRNAs are important …