Oxidative stress and regulated cell death in Parkinson's disease

PA Dionísio, JD Amaral, CMP Rodrigues - Ageing research reviews, 2021 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide. Motor deficits usually associated with PD correlate with dopaminergic axonal …

Neurodegeneration and inflammation—an interesting interplay in Parkinson's disease

C Marogianni, M Sokratous, E Dardiotis… - International journal of …, 2020 - mdpi.com
Parkinson's disease (PD) is a neurodegenerative disorder, caused by, so far, unknown
pathogenetic mechanisms. There is no doubt that pro-inflammatory immune-mediated …

Highly hazardous pesticides and related pollutants: Toxicological, regulatory, and analytical aspects

L Parra-Arroyo, RB González-González… - Science of The Total …, 2022 - Elsevier
The pervasive manifestation and toxicological influence of hazardous pesticides pose
adverse consequences on various environmental matrices and humans, directly via …

Hazardous effects of chemical pesticides on human health–Cancer and other associated disorders

A Sabarwal, K Kumar, RP Singh - Environmental toxicology and …, 2018 - Elsevier
Poisoning from pesticides is a global public health problem and accounts for nearly 300,000
deaths worldwide every year. Exposure to pesticides is inevitable; there are different modes …

[HTML][HTML] Neurotoxicity of pesticides–A link to neurodegeneration

B Vellingiri, M Chandrasekhar, SS Sabari… - Ecotoxicology and …, 2022 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disorder which mainly targets motor
symptoms such as tremor, rigidity, bradykinesia and postural instability. The physiological …

Persistence of pesticides-based contaminants in the environment and their effective degradation using laccase-assisted biocatalytic systems

M Bilal, HMN Iqbal, D Barceló - Science of The Total Environment, 2019 - Elsevier
Inevitable use of pesticides due to modern agricultural practices and the associated
worldwide environmental pollution has called the special attention of the researchers to …

Mitochondrial dysfunction in Parkinson's disease—cause or consequence?

C Chen, DM Turnbull, AK Reeve - Biology, 2019 - mdpi.com
James Parkinson first described the motor symptoms of the disease that took his name over
200 years ago. While our knowledge of many of the changes that occur in this condition has …

Parkinson's disease: a multisystem disorder

HN Costa, AR Esteves, N Empadinhas… - Neuroscience Bulletin, 2023 - Springer
The way sporadic Parkinson's disease (PD) is perceived has undergone drastic changes in
recent decades. For a long time, PD was considered a brain disease characterized by motor …

Neuron-astrocyte interactions in Parkinson's disease

I Miyazaki, M Asanuma - Cells, 2020 - mdpi.com
Parkinson's disease (PD) is the second most common neurodegenerative disease. PD
patients exhibit motor symptoms such as akinesia/bradykinesia, tremor, rigidity, and postural …

[HTML][HTML] Regulation of SIRT3 on mitochondrial functions and oxidative stress in Parkinson's disease

Y Shen, Q Wu, J Shi, S Zhou - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Abstract Sirtuin-3 (SIRT3) is a NAD+-dependent protein deacetylase that is located in
mitochondria, regulating mitochondrial proteins and maintaining cellular antioxidant status …