The two fACEs of the tissue renin-angiotensin systems: implication in cardiovascular diseases
The implication of the renin-angiotensin system (RAS) in the regulation of the cardiovascular
system has been well known for many years. Accordingly, many pharmaceutical inhibitors …
system has been well known for many years. Accordingly, many pharmaceutical inhibitors …
Relation of β2-adrenoceptor haplotype to risk of death and heart transplantation in patients with heart failure
J Shin, MT Lobmeyer, Y Gong, I Zineh… - The American journal of …, 2007 - Elsevier
Heart failure (HF) is characterized by neurohormonal activation of the sympathetic nervous
and renin-angiotensin systems. Genetic polymorphisms in these systems could alter the …
and renin-angiotensin systems. Genetic polymorphisms in these systems could alter the …
Unique Gene Expression Signature in Periadrenal Adipose Tissue Identifies a High Blood Pressure Group in Patients With Cushing Syndrome
BACKGROUND: Cushing syndrome (CS) is a rare disease caused by excess cortisol levels
with high cardiovascular morbidity and mortality. Hypertension in CS promotes …
with high cardiovascular morbidity and mortality. Hypertension in CS promotes …
A pharmacogenetic analysis of determinants of hypertension and blood pressure response to angiotensin-converting enzyme inhibitor therapy in patients with …
JJ Brugts, A Isaacs, MPM De Maat… - Journal of …, 2011 - journals.lww.com
Aims To investigate whether genetic variation in the renin–angiotensin–aldosterone system
(RAAS) and kallikrein-bradykinin pathways is related to hypertension and blood pressure …
(RAAS) and kallikrein-bradykinin pathways is related to hypertension and blood pressure …
Perivascular adipose tissue in vascular function: does locally synthesized angiotensinogen play a role?
EO Cruz-López, E Uijl, AHJ Danser - Journal of Cardiovascular …, 2021 - journals.lww.com
In recent years, perivascular adipose tissue (PVAT) research has gained special attention in
an effort to understand its involvement in vascular function. PVAT is recognized as an …
an effort to understand its involvement in vascular function. PVAT is recognized as an …
Influence of gender and genetic variability on plasma angiotensin peptides
A Reyes-Engel, L Morcillo, FJ Aranda… - Journal of the Renin …, 2006 - journals.sagepub.com
Introduction. We analysed the influence of three polymorphisms of the renin-angiotensin
system (RAS)(I/D from angiotensin-converting enzyme [ACE], M235T from angiotensinogen …
system (RAS)(I/D from angiotensin-converting enzyme [ACE], M235T from angiotensinogen …
ACE inhibitors and angiotensin II receptor antagonists
A Dendorfer, P Dominiak, H Schunkert - Atherosclerosis: Diet and Drugs, 2005 - Springer
The biological actions of angiotensin II (ANG), the most prominent hormone of the renin-
angiotensin-aldosterone system (RAAS), may promote the development of atherosclerosis …
angiotensin-aldosterone system (RAAS), may promote the development of atherosclerosis …
Angiotensinogen M235T polymorphism and the risk of myocardial infarction and stroke among hypertensive patients on ACE-inhibitors or β-blockers
H Schelleman, OH Klungel, J Witteman… - European Journal of …, 2007 - nature.com
Angiotensinogen is an essential component of the renin-angiotensin system. ACE-inhibitors
and β-blockers both have a direct influence on this system. To investigate whether the …
and β-blockers both have a direct influence on this system. To investigate whether the …
Predictors of blood pressure response to the angiotensin receptor blocker candesartan in essential hypertension
VJ Canzanello, E Baranco-Pryor… - American journal of …, 2008 - academic.oup.com
Background Response to antihypertensive drugs varies widely among individuals. Methods
We studied characteristics that might be predictive of blood pressure (BP) response in 203 …
We studied characteristics that might be predictive of blood pressure (BP) response in 203 …
Three single-nucleotide polymorphisms of the angiotensinogen gene and susceptibility to hypertension: single locus genotype vs. haplotype analysis
SJ Wu, FT Chiang, WJ Chen, PH Liu… - Physiological …, 2004 - journals.physiology.org
Although some single polymorphism analyses of the angiotensinogen (AGT) gene have
been found to be associated with hypertension, the results are still inconsistent. The …
been found to be associated with hypertension, the results are still inconsistent. The …