Bevacizumab-induced hypertension: Clinical presentation and molecular understanding

M Li, DL Kroetz - Pharmacology & therapeutics, 2018 - Elsevier
Bevacizumab is a vascular endothelial growth factor-A-specific angiogenesis inhibitor
indicated as an adjunct to chemotherapy for the treatment of several types of cancer …

Renal toxicities of targeted therapies

A Abbas, MM Mirza, AK Ganti, K Tendulkar - Targeted oncology, 2015 - Springer
With the incorporation of targeted therapies in routine cancer therapy, it is imperative that the
array of toxicities associated with these agents be well-recognized and managed, especially …

Preexisting hypertension and cancer therapy: evidence, pathophysiology, and management recommendation

L Koskina, I Andrikou, C Thomopoulos… - Journal of Human …, 2023 - nature.com
Cancer is considered one of the leading causes of mortality worldwide. At the same time,
hypertension is recognized as one of the most common comorbidities in cancer patients …

[HTML][HTML] Research progress on common adverse events caused by targeted therapy for colorectal cancer

B Zhang, C Fang, D Deng, L Xia - Oncology Letters, 2018 - spandidos-publications.com
As targeted drug therapy is increasingly applied in the treatment of colon cancer,
understanding and managing the adverse reactions of patients is becoming increasingly …

Sandwich-like neoadjuvant therapy with bevacizumab for locally advanced rectal cancer: a phase II trial

J Xiao, Z Chen, W Li, Z Yang, Y Huang, J Zheng… - Cancer chemotherapy …, 2015 - Springer
Purpose Current neoadjuvant chemoradiotherapy had limited impact on distal metastasis
and survival in locally advanced rectal cancer. Here, we investigated a new sandwich-like …

VEGF 信号通路抑制剂相关蛋白尿的研究进展

马兴群, 成远, 陈映霞 - 临床肿瘤学杂志, 2015 - manu65.magtech.com.cn
血管内皮生长因子(VEGF) 信号轴在建立和维持肾小球滤过屏障中发挥不可或缺的作用.
蛋白尿是VEGF 信号通路抑制剂的常见不良反应之一, 该类药物可引起肾小球足细胞和肾小球 …

Influence of background cardiovascular risk factors on VEGF inhibitor-related adverse vascular events in patients with non-small cell lung cancer: a retrospective study

T Naito, Y Minegishi, H Shiraishi, T Hoshino… - Journal of Cancer …, 2023 - Springer
Purpose Vascular endothelial growth factor (VEGF) inhibitors are widely used in
chemotherapy for non-small lung cancer (NSCLC). The purpose of the current study was to …

Evaluation of local injection of bevacizumab against triple-negative breast cancer xenograft tumors

X Jiang, QL Zhang, TG Liu, WP Zhao… - Current …, 2019 - ingentaconnect.com
Background and objective: Bevacizumab (BVZ) is a recombinant humanized antibody that
inhibits the vascular endothelial growth factor A (VEGFA) and is used for the treatment of …

贝伐珠单抗对结直肠癌细胞VEGFR1 和VEGFR2 表达的影响

刘洪金, 付艳, 贾森浩, 张莹莹, 张芦芦, 张力文… - 中国肿瘤, 2015 - cqvip.com
[目的] 探讨贝伐珠单抗对结直肠癌细胞血管内皮生长因子(VEGF) 相关受体的影响.[方法] RT-
PCR, Western blotting 检测不同浓度贝伐珠单抗对结直肠癌肿瘤细胞VEGF …

Deterioration of glycemic control contributes to the prevalence of proteinuria among bevacizumab-treated cancer patients with type 2 diabetes mellitus

T Chiba, S Nihei, H Komatsu, M Obara… - Biological and …, 2018 - jstage.jst.go.jp
The objective of this study was to investigate whether improving glycemic control reduces
the prevalence and progression of proteinuria among bevacizumab (BEV)-treated cancer …