Diabetes mellitus is a life-threatening metabolic syndrome. Over the past few decades, the
incidence of diabetes has climbed exponentially. Several therapeutic approaches have …

One of the most promising pharmaceutical research areas is developing advanced delivery
systems for controlled and sustained drug release. The drug delivery system (DDS) can be …

Herein, dual-bioresponsive of Rhein (RH) in promoting colonic mucous damage repair and
controlling inflammatory reactions were combined by the dual-targeting (intestinal epithelial …

Kidney diseases have gradually become a global health burden. Along with the
development of nanotechnology, many hybrids or nanomaterials have been utilized to …

In this study, we developed an advanced colitis-targeted nanoparticles (NPs)-into-yeast cell
wall microparticles (YPs) drug delivery system for ulcerative colitis (UC) therapy. In brief, YPs …

Chitosan–based biomaterials with a low molecular weight (LMW) have been drawn attention
due to the promising applications in the pharmaceutical and food fields. For this reason, the …

This review focuses on nano-structured delivery devices prepared from biodegradable and
biocompatible natural and synthetic polymers, organic raw materials, metals, metal oxides …

Rhein (RH) is a candidate for the treatment of kidney diseases. However, clinical application
of RH is impeded by low aqueous solubility and oral bioavailability. Deoxycholic acid …

Mitochondria are involved in the regulation of apoptosis, making them a promising target for
the development of new anticancer drugs. Doxorubicin (DOX), a chemotherapeutic drug …

Methotrexate (MTX) and diacerein (DIA) are two of the most potent disease-modifying anti-
rheumatic drugs used for the treatment of rheumatoid arthritis (RA). DIA has reflected some …