Chemotherapy remains a cornerstone in the treatment of nonsmall cell lung cancer

R Pirker - Current opinion in oncology, 2020 - journals.lww.com
Chemotherapy remains a cornerstone in the treatment of nonsm... : Current Opinion in
Oncology Chemotherapy remains a cornerstone in the treatment of nonsmall cell lung cancer …

[HTML][HTML] Conquering lung cancer: current status and prospects for the future

R Pirker - Pulmonology, 2020 - Elsevier
Lung cancer is a major global health problem. Several strategies are required to conquer
this cancer. Stricter implementations of tobacco control measures are necessary. Early …

Tislelizumab plus chemotherapy vs chemotherapy alone as first-line treatment for advanced squamous non–small-cell lung cancer: a phase 3 randomized clinical trial

J Wang, S Lu, X Yu, Y Hu, Y Sun, Z Wang… - JAMA …, 2021 - jamanetwork.com
Importance This study demonstrates that tislelizumab in combination with chemotherapy is
associated with improved progression-free survival (PFS) in patients with advanced …

Nanophotonic immunoarray with electrochemically roughened surfaces for handheld detection of secreted PD-L1 to predict immuno-oncology efficacy

S Dey, KM Koo, E Ahmed, M Trau - Lab on a Chip, 2023 - pubs.rsc.org
The analysis of secreted protein biomarkers can be a useful non-invasive method of
predicting or monitoring cancer therapeutic response. The increased level of soluble …

[HTML][HTML] Precision medicine for NSCLC in the era of immunotherapy: new biomarkers to select the most suitable treatment or the most suitable patient

G Rossi, A Russo, M Tagliamento, A Tuzi, O Nigro… - Cancers, 2020 - mdpi.com
In recent years, the evolution of treatments has made it possible to significantly improve the
outcomes of patients with non-small cell lung cancer (NSCLC). In particular, while molecular …

[HTML][HTML] Low-dose ipilimumab plus nivolumab combined with IL-2 and hyperthermia in cancer patients with advanced disease: exploratory findings of a case series of …

R Kleef, R Nagy, A Baierl, V Bacher, H Bojar… - Cancer Immunology …, 2021 - Springer
The 3-year overall survival (OS) rate of patients with previously treated or untreated stage III
or IV melanoma has by now reached 63% using ipilimumab and nivolumab therapy …

Amplifying outcomes: checkpoint inhibitor combinations in first‐line non‐small cell lung cancer

B Melosky, R Juergens, V Hirsh, D McLeod… - The …, 2020 - academic.oup.com
Purpose Lung cancer is one of the most common types of cancer, resulting in approximately
1.8 million deaths worldwide. Immunotherapy using checkpoint inhibitors has become …

[HTML][HTML] Exploring the potential use of a PBMC-based functional assay to identify predictive biomarkers for anti-PD-1 immunotherapy

SM Bacot, TA Harper, RL Matthews, CJ Fennell… - International Journal of …, 2020 - mdpi.com
The absence of reliable, robust, and non-invasive biomarkers for anti-Programmed cell
death protein 1 (PD-1) immunotherapy is an urgent unmet medical need for the treatment of …

[HTML][HTML] Beyond single-cell analysis of metallodrugs by ICP-MS: targeting cellular substructures

A Galé, L Hofmann, N Lüdi, MN Hungerbühler… - International journal of …, 2021 - mdpi.com
Platinum compounds such as cisplatin (cisPt) embody the backbone of combination
chemotherapy protocols against advanced lung cancer. However, their efficacy is primarily …

[HTML][HTML] Granzyme B for predicting the durable clinical benefit of anti-PD-1/PD-L1 immunotherapy in patients with non-small cell lung cancer

JH Chung, JS Ha, J Choi, SM Kwon… - Translational Cancer …, 2022 - ncbi.nlm.nih.gov
Background To identify immunotherapy biomarkers, we examined granzyme B levels in
peripheral blood PD-1+ CD8+ T cells and their relationship with treatment outcomes in …