Maternal and paternal obesity and type 2 diabetes are recognized risk factors for the
development of metabolic dysfunction in offspring, even when the offspring follow a healthful …

Epigenetics can be defined as 'the structural adaptation of chromosomal regions so as to
register, signal, or perpetuate altered activity states.'Increased transcription of key regulatory …

Abnormal conditions during early development adversely affect later health. We investigated
whether maternal exercise could protect offspring from adverse effects of a maternal high-fat …

Poor maternal diet increases the risk of obesity and type 2 diabetes in offspring, adding to
the ever-increasing prevalence of these diseases. In contrast, we find that maternal exercise …

Background: Maternal obesity (MO) impairs maternal and offspring health. Mechanisms and
interventions to prevent adverse maternal and offspring outcomes need to be determined …

The intrauterine environment during pregnancy is a critical factor in the development of
diabetes and obesity in offspring. To determine the effects of maternal exercise during …

Globally, cardiovascular disease remains the leading cause of death. Most concerning is the
rise in cardiovascular risk factors including obesity, diabetes and hypertension among youth …

Scope We investigated the long-term effects of maternal high-fat consumption and post-
weaning exercise on offspring obesity susceptibility and insulin resistance. Methods …

Poor maternal diet can lead to metabolic disease in offspring, whereas maternal exercise
may have beneficial effects on offspring health. In this study, we determined ifmaternal …

Poor maternal environments, such as under-or overnutrition, can increase the risk for the
development of obesity, type 2 diabetes and cardiovascular disease in offspring …