The availability of the human genome sequence and tools for interrogating individual
genomes provide an unprecedented opportunity to apply genetics to medicine. Mendelian …

Although fungal infections contribute substantially to human morbidity and mortality, the
impact of these diseases on human health is not widely appreciated. Moreover, despite the …

The 2013 Infection Prevention and Control (IP&C) Guideline for Cystic Fibrosis (CF) was
commissioned by the CF Foundation as an update of the 2003 Infection Control Guideline …

The identification of small molecules that target specific CFTR variants has ushered in a new
era of treatment for cystic fibrosis (CF), yet optimal, individualized treatment of CF will require …

Sensitization to fungi and long term or uncontrolled fungal infection are associated with poor
control of asthma, the likelihood of more severe disease and complications such as …

Notable progress has been made in the past years in the classification, diagnosis and
treatment of pulmonary aspergillosis. New criteria were proposed by the Working Group of …

Allergic diseases are considered the epidemics of the twentieth century estimated to affect
more than 30% of the population in industrialized countries with a still increasing incidence …

Allergic bronchopulmonary mycosis (ABPM) is a hypersensitivity-mediated disease of
worldwide distribution. We reviewed 143 reported global cases of ABPM due to fungi other …

Aspergillus is a mold that may lead to different clinical pictures, from allergic to invasive
disease, depending on the patient's immune status and structural lung diseases. Chronic …

Eosinophilia can be caused by both infectious and noninfectious processes, many of which
may be clinically indistinguishable. Narrowing the differential diagnosis can be achieved by …