Tranexamic acid–an old drug still going strong and making a revival

L Tengborn, M Blombäck, E Berntorp - Thrombosis research, 2015 - Elsevier
Experience with tranexamic acid, an indirect fibrinolytic inhibitor, started as soon as it was
released from Shosuke Okamoto's lab in the early 1960s. It was first prescribed to females …

Tranexamic acid evidence and controversies: an illustrated review

N Relke, NLJ Chornenki… - Research and practice in …, 2021 - Wiley Online Library
Tranexamic acid (TXA) is an antifibrinolytic agent commonly used for the treatment or
prevention of bleeding. Indications for TXA are diverse, including heavy menstrual bleeding …

Manifestation of tranexamic acid toxicity in chronic kidney disease and kidney transplant patients: a report of four cases and review of literature

TKW Ma, KM Chow, BCH Kwan, CB Leung… - …, 2017 - Wiley Online Library
Aim Tranexamic acid (TXA) is a synthetic anti‐fibrinolytic agent commonly used for the
prevention and treatment of bleeding disorders. The aim of this study is to describe the …

Tranexamic acid in total knee arthroplasty.

CR Bailey - Anaesthesia, 2023 - search.ebscohost.com
The authors found a dose-dependent surgical site infection risk in blood-transfused patients
and hypothesised that those undergoing knee arthroplasty who receive multiple doses of …

Medical therapy with tranexamic acid in autosomal dominant polycystic kidney disease patients with severe haematuria

R Peces, A Aguilar, C Vega, E Cuesta… - Nefrología (English …, 2012 - revistanefrologia.com
Antecedentes: En la poliquistosis renal autosómica dominante (PQRAD), la hematuria
macroscópica por la rotura de quistes renales es una manifestación habitual, que puede ser …

Challenging clinical scenarios for therapeutic anticoagulation: A practical approach

KL Martens, SE Dekker, M Crowe, TG DeLoughery… - Thrombosis research, 2022 - Elsevier
Therapeutic anticoagulation remains a fundamental backbone in the treatment and
prevention of venous thromboembolism. However, while modern therapies are increasingly …

Treatment of persistent gross hematuria with tranexamic acid in autosomal dominant polycystic kidney disease

Q Yao, M Wu, J Zhou, M Zhou, D Chen, L Fu… - Kidney and Blood …, 2017 - karger.com
Abstract Background/Aims: In this retrospective study we aimed to compare the effect of
tranexamic acid (TXA) vs etamsylate, two hemostatic agents, on hematuria duration in …

The Crosstalk between Nephropathy and Coagulation Disorder: Pathogenesis, Treatment, and Dilemmas

Z Qiu, X Pang, Q Xiang, Y Cui - Journal of the American Society of …, 2023 - journals.lww.com
The interaction between the kidney and the coagulation system greatly affects each other
because of the abundant vessel distribution and blood perfusion in the kidney. Clinically, the …

[PDF][PDF] Tratamiento eficaz de la arteriolopatía urémica calcificante con bifosfonatos

JV Torregrosa, CE Durán, X Barros, M Blasco… - Nefrología …, 2012 - SciELO Espana
TORREGROSA, José V. et al. Tratamiento eficaz de la arteriolopatía urémica calcificante
con bifosfonatos. Nefrología (Madr.)[online]. 2012, vol. 32, n. 3, pp. 329-334. ISSN 0211 …

Evaluation and management of gross hematuria in autosomal dominant polycystic kidney disease: a point of care guide for practicing internists

B Bhasin, M Alzubaidi, JCQ Velez - The American Journal of the Medical …, 2018 - Elsevier
Gross hematuria is common in autosomal dominant polycystic kidney disease (ADPKD). It is
an alarming symptom and may be the first manifestation of ADPKD. Cyst hemorrhage is a …