The mammalian brain expresses several classes of noncoding RNAs (ncRNAs), including
long ncRNAs (lncRNAs), circular RNAs (circRNAs), and microRNAs (miRNAs). These …

Autophagy is an important biological mechanism involved in the regulation of numerous
fundamental cellular processes that are mainly associated with cellular growth and …

Remote ischemic conditioning (RIC) is a promising therapeutic approach for ischemic stroke
patients. It has been proven that RIC reduces infarct size and improves functional outcomes …

Despite decades of formidable exploration, multi-organ ischemia-reperfusion injury (IRI)
encountered, particularly amongst elderly patients with clinical scenarios, such as age …

Ischemic stroke (IS) is a central nervous system neurological disorder ascribed to an acute
focal trauma, with high mortality and disability, leading to a heavy burden on family and …

Stroke is one of the main causes of neurological disability worldwide and the second cause
of death in people over 65 years old, resulting in great economic and social burden …

Oxidative stress is a key pathogenic factor of cerebral ischemia/reperfusion (I/R) injury.
MicroRNA-32-3p (miR-32-3p) plays critical roles in regulating ischemic diseases; however …

Autophagy, a catabolic degradation system, is utilized for destroying and recycling the
damaged or unnecessary cellular components. Brain plasticity refers to the remarkable …

Objectives This study aims to investigate the neuroprotective effects of curcumin analogues,
7-(4-Hydroxy-3-methoxyphenyl)-1-phenyl-4 E-hepten-3-one (AO-2) on oxygen–glucose …

Bone marrow-derived mesenchymal stem cells (BMSCs) transplantation is a promising
therapeutic strategy for cerebral ischemia/reperfusion (I/R) injury; however, the clinical …