Aging, oxidative stress and degenerative diseases: mechanisms, complications and emerging therapeutic strategies

MR Chaudhary, S Chaudhary, Y Sharma, TA Singh… - Biogerontology, 2023 - Springer
Aging accompanied by several age-related complications, is a multifaceted inevitable
biological progression involving various genetic, environmental, and lifestyle factors. The …

[HTML][HTML] Antioxidant therapy in oxidative stress-induced neurodegenerative diseases: Role of nanoparticle-based drug delivery systems in clinical translation

A Ashok, SS Andrabi, S Mansoor, Y Kuang, BK Kwon… - Antioxidants, 2022 - mdpi.com
Free radicals are formed as a part of normal metabolic activities but are neutralized by the
endogenous antioxidants present in cells/tissue, thus maintaining the redox balance. This …

[HTML][HTML] Association between life's essential 8 and biological ageing among US adults

R Zhang, M Wu, W Zhang, X Liu, J Pu, T Wei… - Journal of translational …, 2023 - Springer
Background Biological ageing is tightly linked to cardiovascular disease (CVD). We aimed to
investigate the relationship between Life's Essential 8 (LE8), a currently updated measure of …

[HTML][HTML] Effect of methionine restriction on aging: its relationship to oxidative stress

M Kitada, Y Ogura, I Monno, J Xu, D Koya - Biomedicines, 2021 - mdpi.com
Enhanced oxidative stress is closely related to aging and impaired metabolic health and is
influenced by diet-derived nutrients and energy. Recent studies have shown that methionine …

Hydroxysafflor yellow A and anhydrosafflor yellow B alleviate ferroptosis and parthanatos in PC12 cells injured by OGD/R

G Chen, C Li, L Zhang, J Yang, H Meng, H Wan… - Free Radical Biology and …, 2022 - Elsevier
Ferroptosis and parthanatos are two types of programmed cell death associated with
cerebral ischemia. There is a sizeable interest in seeking chemical components for the …

[HTML][HTML] A narrative review of lifestyle risk factors and the role of oxidative stress in age-related hearing loss

D Tang, Y Tran, P Dawes, B Gopinath - Antioxidants, 2023 - mdpi.com
Age-related hearing loss affects a significant proportion of adults aged 60 years and above,
with a prevalence of 65%. This condition has a negative impact on both physical and mental …

Lifestyle medicine as a treatment for resistant hypertension

F Ribeiro, M Teixeira, AJ Alves, A Sherwood… - Current hypertension …, 2023 - Springer
Abstract Purpose of Review Approximately 10% of the adults with hypertension fail to
achieve the recommended blood pressure treatment targets on 3 antihypertensive …

Adipokines: Deciphering the cardiovascular signature of adipose tissue

JC Galley, S Singh, WMC Awata, JV Alves… - Biochemical …, 2022 - Elsevier
Obesity and hypertension are intimately linked due to the various ways that the important
cell types such as vascular smooth muscle cells (VSMC), endothelial cells (EC), immune …

[HTML][HTML] Endothelial dysfunction, platelet hyperactivity, hypertension, and the metabolic syndrome: molecular insights and combating strategies

D Das, NR Shruthi, A Banerjee, G Jothimani… - Frontiers in …, 2023 - frontiersin.org
Metabolic syndrome (MetS) is a multifaceted condition that increases the possibility of
developing atherosclerotic cardiovascular disease. MetS includes obesity, hypertension …

D-limonene (5 (one-methyl-four-[1-methylethenyl]) cyclohexane) diminishes CCl4-induced cardiac toxicity by alleviating oxidative stress, inflammatory and cardiac …

RM AlSaffar, S Rashid, SB Ahmad, MU Rehman… - Redox …, 2022 - Taylor & Francis
Background: The cardiovascular crisis is advancing rapidly throughout the world. A large
number of studies have shown that plant polyphenols affect major mechanisms involved in …