The intrinsically disordered region from PP2C phosphatases functions as a conserved CO2 sensor

M Zhang, C Zhu, Y Duan, T Liu, H Liu, C Su, Y Lu - Nature cell biology, 2022 - nature.com
Carbon dioxide not only plays a central role in the carbon cycle, but also acts as a crucial
signal in living cells. Adaptation to changing CO2 concentrations is critical for all organisms …

Zinc Finger Proteins in the Human Fungal Pathogen Cryptococcus neoformans

YH Li, TB Liu - International journal of molecular sciences, 2020 - mdpi.com
Zinc is one of the essential trace elements in eukaryotes and it is a critical structural
component of a large number of proteins. Zinc finger proteins (ZNFs) are zinc-finger domain …

[HTML][HTML] Role of F-box Protein Cdc4 in Fungal Virulence and Sexual Reproduction of Cryptococcus neoformans

T Wu, CL Fan, LT Han, YB Guo, TB Liu - Frontiers in Cellular and …, 2022 - frontiersin.org
Cryptococcus neoformans is an opportunistic yeast-like pathogen that mainly infects
immunocompromised individuals and causes fatal meningitis. Sexual reproduction can …

Pleiotropic roles of LAMMER kinase, Lkh1 in stress responses and virulence of Cryptococcus neoformans

S Kwon, Y Choi, ES Kim, KT Lee, YS Bahn… - Frontiers in Cellular …, 2024 - frontiersin.org
Dual-specificity LAMMER kinases are highly evolutionarily conserved in eukaryotes and
play pivotal roles in diverse physiological processes, such as growth, differentiation, and …

Transcriptional dynamics of genes purportedly involved in the control of meiosis, carbohydrate, and secondary metabolism during sporulation in Ganoderma lucidum

M Cai, X Liang, Y Liu, H Hu, Y Xie, S Chen, X Gao, X Li… - Genes, 2021 - mdpi.com
Ganoderma lucidum spores (GLS), the mature germ cells ejected from the abaxial side of
the pileus, have diverse pharmacological effects. However, the genetic regulation of …

The Vacuolar Morphogenesis Protein Vam6-Like Protein Vlp1 Is Required for Pathogenicity of Cryptococcus neoformans

CL Fan, TB Liu - Journal of Fungi, 2021 - mdpi.com
Cryptococcus neoformans is an encapsulated yeast pathogen that infects
immunocompromised patients to cause fungal meningitis, resulting in hundreds of …

Up-regulation of Hsa_circ_0008792 inhibits osteosarcoma cell invasion and migration and promotes apoptosis by regulating Hsa-miR-711/ZFP1

L Chen, Y Shan, H Zhang, H Wang… - OncoTargets and …, 2020 - Taylor & Francis
Objective Circular RNA is a newly discovered non-coding RNA. It plays an important role in
regulating gene expression, and may take part in tumor progression. This study aimed to …

[HTML][HTML] The F-Box Protein Fbp1 Regulates Virulence of Cryptococcus neoformans Through the Putative Zinc-Binding Protein Zbp1

LT Han, YJ Wu, TB Liu - Frontiers in Cellular and Infection …, 2021 - frontiersin.org
The ubiquitin-proteasome system (UPS) is the major protein turnover mechanism that plays
an important role in regulating various cellular functions. F-box proteins are the key proteins …

Ubiquitin Degradation of the AICAR Transformylase/IMP Cyclohydrolase Ade16 Regulates the Sexual Reproduction of Cryptococcus neoformans

L Han, Y Wu, S Xiong, T Liu - Journal of Fungi, 2023 - mdpi.com
F-box protein is a key protein of the SCF E3 ubiquitin ligase complex, responsible for
substrate recognition and degradation through specific interactions. Previous studies have …

The Role of Oxidoreductase-Like Protein Olp1 in Sexual Reproduction and Virulence of Cryptococcus neoformans

QK Yu, LT Han, YJ Wu, TB Liu - Microorganisms, 2020 - mdpi.com
Cryptococcus neoformans is a basidiomycete human fungal pathogen causing lethal
meningoencephalitis, mainly in immunocompromised patients. Oxidoreductases are a class …