Autonomic control of cerebral blood flow: fundamental comparisons between peripheral and cerebrovascular circulations in humans

JL Koep, CE Taylor, JS Coombes… - The Journal of …, 2022 - Wiley Online Library
Understanding the contribution of the autonomic nervous system to cerebral blood flow
(CBF) control is challenging, and interpretations are unclear. The identification of calcium …

[HTML][HTML] “THE MANTLE” bundle for minimizing cerebral hypoxia in severe traumatic brain injury

DA Godoy, F Murillo-Cabezas, JI Suarez, R Badenes… - Critical Care, 2023 - Springer
To ensure neuronal survival after severe traumatic brain injury, oxygen supply is essential.
Cerebral tissue oxygenation represents the balance between oxygen supply and …

Systemic physiology augmented functional near-infrared spectroscopy: a powerful approach to study the embodied human brain

F Scholkmann, I Tachtsidis, M Wolf, U Wolf - Neurophotonics, 2022 - spiedigitallibrary.org
In this Outlook paper, we explain why an accurate physiological interpretation of functional
near-infrared spectroscopy (fNIRS) neuroimaging signals is facilitated when systemic …

[HTML][HTML] The lower limit of reactivity as a potential individualised cerebral perfusion pressure target in traumatic brain injury: a CENTER-TBI high-resolution sub-study …

E Beqiri, FA Zeiler, A Ercole, MM Placek, J Tas… - Critical Care, 2023 - Springer
Background A previous retrospective single-centre study suggested that the percentage of
time spent with cerebral perfusion pressure (CPP) below the individual lower limit of …

Quantification of dynamic cerebral autoregulation: welcome to the jungle!

P Brassard, MA Roy, JS Burma, L Labrecque… - Clinical Autonomic …, 2023 - Springer
Purpose Patients with dysautonomia often experience symptoms such as dizziness,
syncope, blurred vision and brain fog. Dynamic cerebral autoregulation, or the ability of the …

[HTML][HTML] Clinical targeting of the cerebral oxygen cascade to improve brain oxygenation in patients with hypoxic–ischaemic brain injury after cardiac arrest

RL Hoiland, C Robba, DK Menon, G Citerio… - Intensive Care …, 2023 - Springer
The cerebral oxygen cascade includes three key stages:(a) convective oxygen delivery
representing the bulk flow of oxygen to the cerebral vascular bed;(b) diffusion of oxygen from …

[HTML][HTML] Towards autoregulation-oriented management after traumatic brain injury: increasing the reliability and stability of the CPPopt algorithm

E Beqiri, A Ercole, MJH Aries, MM Placek, J Tas… - Journal of clinical …, 2023 - Springer
Abstract Purpose CPPopt denotes a Cerebral Perfusion Pressure (CPP) value at which the
Pressure-Reactivity index, reflecting the global state of Cerebral Autoregulation, is best …

On the use and misuse of cerebral hemodynamics terminology using transcranial Doppler ultrasound: a call for standardization

RJ Skow, RM Brothers… - American Journal …, 2022 - journals.physiology.org
Cerebral hemodynamics, eg, cerebral blood flow, can be measured and quantified using
many different methods, with transcranial Doppler ultrasound (TCD) being one of the most …

Continuous time-domain cerebrovascular reactivity metrics and discriminate capacity for the upper and lower limits of autoregulation: a scoping review of the animal …

AS Sainbhi, L Froese, A Gomez, C Batson… - Neurotrauma …, 2021 - liebertpub.com
Over a wide range of systemic arterial pressures, cerebral blood flow (CBF) is regulated
fairly constantly by the cerebral vessels in a process termed cerebral autoregulation (CA) …

[HTML][HTML] Multimodal and autoregulation monitoring in the neurointensive care unit

JR Vitt, NE Loper, S Mainali - Frontiers in neurology, 2023 - frontiersin.org
Given the complexity of cerebral pathology in patients with acute brain injury, various
neuromonitoring strategies have been developed to better appreciate physiologic …