Despite an ever-growing prevalence and increasing economic burden of Alzheimer's
disease (AD) and Parkinson's disease (PD), recent advances in drug development have …

Alzheimer's disease (AD) is characterized by the accumulation of hyperphosphorylated tau
and amyloid-β (Aβ) protein resulting in synaptic loss and apoptosis. Aβ and tau deposition …

Currently, there is no disease-modifying treatment available for Alzheimer's and Parkinson's
disease (AD and PD) and that includes the highly controversial approval of the Aβ-targeting …

Polycystic ovary syndrome (PCOS) is a disease in which endocrine metabolic abnormalities
coexist with reproductive system abnormalities, with the main clinical manifestations …

The ketogenic diet (KD) is a low-carbohydrate, high-fat and adequate-protein diet. As a diet
mimicking fasting, it triggers the production of ketone bodies (KBs) and brings the body into …

Abstract Background Bisphenol A (BPA), a ubiquitous environmental endocrine disruptor,
has been extensively demonstrated to be associated with metabolic disorders, including …

Insulin resistance is common in type 2 diabetes mellitus (T2DM), neurodegenerative
diseases, cardiovascular diseases, kidney diseases, and polycystic ovary syndrome …

Intermittent fasting (IF) has been studied for its effects on lifespan and the prevention or
delay of age-related diseases upon the regulation of metabolic pathways. Mitochondria …

The gene encoding proprotein convertase subtilisin/kexin type 9 (PCSK9) and its protein
product have been widely studied for their role in cholesterol and lipid metabolism. PCSK9 …

Alzheimer's disease (AD) and Parkinson's disease (PD) are the most frequent
neurodegenerative disorders. Despite their pathophysiological and clinical differences, they …