Red blood cell distribution width: a novel predictive indicator for cardiovascular and cerebrovascular diseases

N Li, H Zhou, Q Tang - Disease markers, 2017 - Wiley Online Library
The red blood cell distribution width (RDW) obtained from a standard complete blood count
(CBC) is a convenient and inexpensive biochemical parameter representing the variability in …

Red blood cell metabolism in vivo and in vitro

A D'Alessandro, AT Anastasiadi, VL Tzounakas… - Metabolites, 2023 - mdpi.com
Red blood cells (RBC) are the most abundant cell in the human body, with a central role in
oxygen transport and its delivery to tissues. However, omics technologies recently revealed …

An update on red blood cell storage lesions, as gleaned through biochemistry and omics technologies

A D'Alessandro, AG Kriebardis, S Rinalducci… - …, 2015 - Wiley Online Library
Red blood cell (RBC) aging in the blood bank is characterized by the accumulation of a
significant number of biochemical and morphologic alterations. Recent mass spectrometry …

Red cell distribution width in relation to incidence of stroke and carotid atherosclerosis: a population-based cohort study

M Söderholm, Y Borné, B Hedblad, M Persson… - PloS one, 2015 - journals.plos.org
Background Increased red cell distribution width (RDW) has been related to poor prognosis
in patients with cardiovascular disease, and is a predictor of cardiovascular mortality in the …

Acute cycling exercise induces changes in red blood cell deformability and membrane lipid remodeling

T Nemkov, SC Skinner, E Nader, D Stefanoni… - International journal of …, 2021 - mdpi.com
Here we describe the effects of a controlled, 30 min, high-intensity cycling test on blood
rheology and the metabolic profiles of red blood cells (RBCs) and plasma from well-trained …

[HTML][HTML] The mechanism of formation, structure and physiological relevance of covalent hemoglobin attachment to the erythrocyte membrane

EM Welbourn, MT Wilson, A Yusof, MV Metodiev… - Free Radical Biology …, 2017 - Elsevier
Covalent hemoglobin binding to membranes leads to band 3 (AE1) clustering and the
removal of erythrocytes from the circulation; it is also implicated in blood storage lesions …

Red blood cell deformability is expressed by a set of interrelated membrane proteins

G Barshtein, A Gural, D Arbell, R Barkan… - International Journal of …, 2023 - mdpi.com
Red blood cell (RBC) deformability, expressing their ability to change their shape, allows
them to minimize their resistance to flow and optimize oxygen delivery to the tissues. RBC …

The multiple facets of iron recycling

P Slusarczyk, K Mleczko-Sanecka - Genes, 2021 - mdpi.com
The production of around 2.5 million red blood cells (RBCs) per second in erythropoiesis is
one of the most intense activities in the body. It continuously consumes large amounts of …

Donor‐dependent aging of young and old red blood cell subpopulations: Metabolic and functional heterogeneity

O Mykhailova, C Olafson, TR Turner… - …, 2020 - Wiley Online Library
Background Characteristics of red blood cells (RBCs) are influenced by donor variability.
This study assessed quality and metabolomic variables of RBC subpopulations of varied …

[HTML][HTML] Phosphatidylserine exposure in human red blood cells depending on cell age

MC Wesseling, L Wagner-Britz, H Huppert… - Cellular physiology and …, 2016 - karger.com
Background/Aims: The exposure of phosphatidylserine (PS) on the outer membrane leaflet
of red blood cells (RBCs) serves as a signal for suicidal erythrocyte death or eryptosis, which …