[HTML][HTML] The role of the ATP-binding cassette A1 (ABCA1) in human disease
L Jacobo-Albavera, M Domínguez-Pérez… - International journal of …, 2021 - mdpi.com
Cholesterol homeostasis is essential in normal physiology of all cells. One of several
proteins involved in cholesterol homeostasis is the ATP-binding cassette transporter A1 …
proteins involved in cholesterol homeostasis is the ATP-binding cassette transporter A1 …
[HTML][HTML] Tim-4 in health and disease: Friend or foe?
W Liu, L Xu, X Liang, X Liu, Y Zhao, C Ma… - Frontiers in …, 2020 - frontiersin.org
T-cell immunoglobulin and mucin domain containing 4 (Tim-4) is a phosphatidylserine
receptor and is selectively expressed on antigen presenting cells. Recently, Tim-4 was …
receptor and is selectively expressed on antigen presenting cells. Recently, Tim-4 was …
Tim-4 inhibits NLRP3 inflammasome via the LKB1/AMPKα pathway in macrophages
W Liu, F Bai, H Wang, Y Liang, X Du, C Liu… - The Journal of …, 2019 - journals.aai.org
Nonalcoholic fatty liver disease (NAFLD), characterized by excessive inflammation and lipid
deposition, is one of the most common metabolic liver diseases. The expression of NLRP3 …
deposition, is one of the most common metabolic liver diseases. The expression of NLRP3 …
Pharmacogenetic considerations in the treatment of Alzheimer's disease
R Cacabelos, C Torrellas, O Teijido… - Pharmacogenomics, 2016 - Future Medicine
The practical pharmacogenetics of Alzheimer's disease (AD) is circumscribed to
acetylcholinesterase inhibitors (AChEIs) and memantine. However, pharmacogenetic …
acetylcholinesterase inhibitors (AChEIs) and memantine. However, pharmacogenetic …
[HTML][HTML] Association of apolipoprotein E gene polymorphisms with blood lipids and their interaction with dietary factors
IM Shatwan, KH Winther, B Ellahi, P Elwood… - Lipids in health and …, 2018 - Springer
Background Several candidate genes have been identified in relation to lipid metabolism,
and among these, lipoprotein lipase (LPL) and apolipoprotein E (APOE) gene …
and among these, lipoprotein lipase (LPL) and apolipoprotein E (APOE) gene …
[HTML][HTML] Associations between liver X receptor polymorphisms and blood lipids: A systematic review and meta-analysis
Genetic susceptibility to dyslipidaemia remains incompletely understood. The liver X
receptors (LXRs), members of the nuclear receptor superfamily of ligand dependent …
receptors (LXRs), members of the nuclear receptor superfamily of ligand dependent …
Opportunities in pharmacogenomics for the treatment of Alzheimer's disease
R Cacabelos, C Torrellas, I Carrera - Future Neurology, 2015 - Taylor & Francis
In Alzheimer's disease (AD), approximately 10–20% of direct costs are associated with
pharmacological treatment. Pharmacogenomics account for 30–90% variability in …
pharmacological treatment. Pharmacogenomics account for 30–90% variability in …
Association between the TIMD4-HAVCR1 variants and serum lipid levels, coronary heart disease and ischemic stroke risk and atorvastatin lipid-lowering efficacy
QH Zhang, RX Yin, WX Chen, XL Cao… - Bioscience …, 2018 - portlandpress.com
Little is known about the association of the TIMD4 (T-cell immunoglobulin and mucin domain
4 gene)-HAVCR1 (hepatitis A virus cellular receptor 1) variants and lipid metabolism, the …
4 gene)-HAVCR1 (hepatitis A virus cellular receptor 1) variants and lipid metabolism, the …
Hepatic ABC transporters and triglyceride metabolism
Hepatic ABC transporters and triglyceride metabolism : Current Opinion in Lipidology Hepatic
ABC transporters and triglyceride metabolism : Current Opinion in Lipidology Log in or Register …
ABC transporters and triglyceride metabolism : Current Opinion in Lipidology Log in or Register …
Association of single nucleotide polymorphisms with dyslipidemia and risk of metabolic disorders in the State of Qatar
D Al‐Sharshani, D Velayutham… - … Genetics & Genomic …, 2023 - Wiley Online Library
Background Dyslipidemia is recognized as one of the risk factors of cardiovascular diseases
(CVDs), type 2 diabetes mellitus (T2DM), and non‐alcoholic fatty liver disease (NAFLD) …
(CVDs), type 2 diabetes mellitus (T2DM), and non‐alcoholic fatty liver disease (NAFLD) …