Small molecule DCN1 inhibitors and therapeutic methods using the same
Compounds of formula (I) as inhibitors of DCN1 and compositions containing the same are
disclosed. Methods of using the DCN1 inhibitors in the treatment of diseases and conditions …
disclosed. Methods of using the DCN1 inhibitors in the treatment of diseases and conditions …
Expanding the liver small-RNA transcriptome: discovery of novel and oncofetal non-coding RNAs with roles in hepatocellular carcinoma
B de Carvalho Minatel - 2019 - open.library.ubc.ca
The major clinical challenges for liver cancer patients are the late stage of diagnosis and the
lack of therapeutic targets with low hepatotoxicity. Hepatocellular carcinoma (HCC) accounts …
lack of therapeutic targets with low hepatotoxicity. Hepatocellular carcinoma (HCC) accounts …
Development of Novel Chemical Probes for the Elucidation of Bacterial and Viral Pathogenesis and Mechanisms of Infection
MA Lafreniere - 2018 - ruor.uottawa.ca
Bioactive small molecules have been a major source of therapeutics for the treatment of
human disease. Advances in synthetic and semi-synthetic methods have greatly expanded …
human disease. Advances in synthetic and semi-synthetic methods have greatly expanded …