[PDF][PDF] Review on epidermal growth factor receptor (EGFR) structure, signaling pathways, interactions, and recent updates of EGFR inhibitors
The epidermal growth factor receptor (EGFR) belongs to the ERBB family of tyrosine kinase
receptors. EGFR signaling cascade is a key regulator in cell proliferation, differentiation …
receptors. EGFR signaling cascade is a key regulator in cell proliferation, differentiation …
FGF receptors: cancer biology and therapeutics
M Katoh, H Nakagama - Medicinal research reviews, 2014 - Wiley Online Library
Fibroblast growth factors (FGFs) are involved in a variety of cellular processes, such as
stemness, proliferation, anti‐apoptosis, drug resistance, and angiogenesis. Here, FGF …
stemness, proliferation, anti‐apoptosis, drug resistance, and angiogenesis. Here, FGF …
[HTML][HTML] Nanoparticle-based drug delivery systems targeting cancer cell surfaces
L Hong, W Li, Y Li, S Yin - RSC advances, 2023 - pubs.rsc.org
Traditional cancer chemotherapy easily produces serious toxic and side effects due to the
lack of specific selection of tumor cells, which restricts its curative effect. Targeted delivery …
lack of specific selection of tumor cells, which restricts its curative effect. Targeted delivery …
Review on EGFR inhibitors: critical updates
Epidermal Growth Factor Receptor (EGFR) is a transmembrane glycoprotein that constitutes
one of the four members of ErbB family of tyrosine kinase receptors. Activation of EGFR …
one of the four members of ErbB family of tyrosine kinase receptors. Activation of EGFR …
Development of hypoxia-activated PROTAC exerting a more potent effect in tumor hypoxia than in normoxia
W Cheng, S Li, X Wen, S Han, S Wang, H Wei… - Chemical …, 2021 - pubs.rsc.org
Hypoxia is a hallmark of many solid tumors, and it causes the overexpression of a variety of
proteins including the epidermal growth factor receptor (EGFR). Many antitumor prodrugs …
proteins including the epidermal growth factor receptor (EGFR). Many antitumor prodrugs …
[HTML][HTML] STAT3 as a target for inducing apoptosis in solid and hematological tumors
K Al Zaid Siddiquee, J Turkson - Cell research, 2008 - nature.com
Studies in the past few years have provided compelling evidence for the critical role of
aberrant Signal Transducer and Activator of Transcription 3 (STAT3) in malignant …
aberrant Signal Transducer and Activator of Transcription 3 (STAT3) in malignant …
Therapeutic progression of quinazolines as targeted chemotherapeutic agents
R Bansal, A Malhotra - European Journal of Medicinal Chemistry, 2021 - Elsevier
Presently cancer is a grave health issue with predominance beyond restrictions. It can affect
any organ of the body. Most of the available chemotherapeutic drugs are highly toxic, not …
any organ of the body. Most of the available chemotherapeutic drugs are highly toxic, not …
Antitumoral activity of snake venom proteins: new trends in cancer therapy
LA Calderon, JC Sobrinho, KD Zaqueo… - BioMed research …, 2014 - Wiley Online Library
For more than half a century, cytotoxic agents have been investigated as a possible
treatment for cancer. Research on animal venoms has revealed their high toxicity on tissues …
treatment for cancer. Research on animal venoms has revealed their high toxicity on tissues …
The anticancer effect of probiotic Bacillus polyfermenticus on human colon cancer cells is mediated through ErbB2 and ErbB3 inhibition
EL Ma, YJ Choi, J Choi, C Pothoulakis… - … journal of cancer, 2010 - Wiley Online Library
A wealth of data implicates that ErbB receptors have essential roles in tumor development.
Probiotic bacteria are known to exert an anticancer activity in animal studies. Bacillus …
Probiotic bacteria are known to exert an anticancer activity in animal studies. Bacillus …
Localized delivery of growth factors for periodontal tissue regeneration: role, strategies, and perspectives
FM Chen, RM Shelton, Y Jin… - Medicinal Research …, 2009 - Wiley Online Library
Difficulties associated with achieving predictable periodontal regeneration, means that novel
techniques need to be developed in order to regenerate the extensive soft and hard tissue …
techniques need to be developed in order to regenerate the extensive soft and hard tissue …