[HTML][HTML] Anxiety, depression, and the microbiome: a role for gut peptides

G Lach, H Schellekens, TG Dinan, JF Cryan - Neurotherapeutics, 2018 - Elsevier
The complex bidirectional communication between the gut and the brain is finely
orchestrated by different systems, including the endocrine, immune, autonomic, and enteric …

[HTML][HTML] Social brain, social dysfunction and social withdrawal

S Porcelli, N Van Der Wee, S van der Werff… - Neuroscience & …, 2019 - Elsevier
The human social brain is complex. Current knowledge fails to define the neurobiological
processes underlying social behaviour involving the (patho-) physiological mechanisms that …

Survival of the Friendliest: Homo sapiens Evolved via Selection for Prosociality

B Hare - Annual review of psychology, 2017 - annualreviews.org
The challenge of studying human cognitive evolution is identifying unique features of our
intelligence while explaining the processes by which they arose. Comparisons with …

A randomized placebo-controlled pilot trial shows that intranasal vasopressin improves social deficits in children with autism

KJ Parker, O Oztan, RA Libove, N Mohsin… - Science translational …, 2019 - science.org
The social impairments of autism spectrum disorder (ASD) have a major impact on quality of
life, yet there are no medications that effectively treat these core social behavior deficits …

Interactions between central nervous system and peripheral metabolic organs

W Zeng, F Yang, WL Shen, C Zhan, P Zheng… - Science China Life …, 2022 - Springer
According to Descartes, minds and bodies are distinct kinds of “substance”, and they cannot
have causal interactions. However, in neuroscience, the two-way interaction between the …

Developmental programming of oxytocin through variation in early-life stress: Four meta-analyses and a theoretical reinterpretation

BJ Ellis, AJ Horn, CS Carter, MH van IJzendoorn… - Clinical Psychology …, 2021 - Elsevier
Despite evidence supporting a role for oxytocin (OT) in regulating social behavior,
surprisingly little is known about how this neuropeptide is calibrated during development …

Elucidating solution structures of cyclic peptides using molecular dynamics simulations

J Damjanovic, J Miao, H Huang, YS Lin - Chemical reviews, 2021 - ACS Publications
Protein–protein interactions are vital to biological processes, but the shape and size of their
interfaces make them hard to target using small molecules. Cyclic peptides have shown …

Selenium in bodily homeostasis: hypothalamus, hormones, and highways of communication

P Toh, JL Nicholson, AM Vetter, MJ Berry… - International journal of …, 2022 - mdpi.com
The ability of the body to maintain homeostasis requires constant communication between
the brain and peripheral tissues. Different organs produce signals, often in the form of …

Toxoplasma Modulates Signature Pathways of Human Epilepsy, Neurodegeneration & Cancer

HM Ngô, Y Zhou, H Lorenzi, K Wang, TK Kim… - Scientific Reports, 2017 - nature.com
One third of humans are infected lifelong with the brain-dwelling, protozoan parasite,
Toxoplasma gondii. Approximately fifteen million of these have congenital toxoplasmosis …

Pathophysiology of drug-induced hyponatremia

GH Kim - Journal of Clinical Medicine, 2022 - mdpi.com
Drug-induced hyponatremia caused by renal water retention is mainly due to syndrome of
inappropriate antidiuresis (SIAD). SIAD can be grouped into syndrome of inappropriate …