Lytic activity by temperate phages of Pseudomonas aeruginosa in long-term cystic fibrosis chronic lung infections
CE James, EV Davies, JL Fothergill… - The ISME …, 2015 - academic.oup.com
Pseudomonas aeruginosa is the most common bacterial pathogen infecting the lungs of
cystic fibrosis (CF) patients. The transmissible Liverpool epidemic strain (LES) harbours …
cystic fibrosis (CF) patients. The transmissible Liverpool epidemic strain (LES) harbours …
[HTML][HTML] The potential of phage therapy in cystic fibrosis: Essential human-bacterial-phage interactions and delivery considerations for use in Pseudomonas …
As antimicrobial-resistant microbes become increasingly common and a significant global
issue, novel approaches to treating these infections particularly in those at high risk are …
issue, novel approaches to treating these infections particularly in those at high risk are …
Why? – Successful Pseudomonas aeruginosa clones with a focus on clone C
The environmental species Pseudomonas aeruginosa thrives in a variety of habitats. Within
the epidemic population structure of P. aeruginosa, occassionally highly successful clones …
the epidemic population structure of P. aeruginosa, occassionally highly successful clones …
Filamentous prophage Pf4 promotes genetic exchange in Pseudomonas aeruginosa
TT Pei, H Luo, Y Wang, H Li, XY Wang… - The ISME …, 2024 - academic.oup.com
Filamentous prophages are widespread among bacteria and play crucial functions in
virulence, antibiotic resistance, and biofilm structures. The filamentous Pf4 particles …
virulence, antibiotic resistance, and biofilm structures. The filamentous Pf4 particles …
Mechanistic analysis of a synthetic inhibitor of the Pseudomonas aeruginosa LasI quorum-sensing signal synthase
O Lidor, A Al-Quntar, EC Pesci, D Steinberg - Scientific reports, 2015 - nature.com
Pseudomonas aeruginosa is an opportunistic Gram-negative pathogen responsible for
many human infections. LasI is an acyl-homoserine lactone synthase that produces a …
many human infections. LasI is an acyl-homoserine lactone synthase that produces a …
[HTML][HTML] Persistence and genetic adaptation of Pseudomonas aeruginosa in patients with chronic obstructive pulmonary disease
J Eklöf, MA Misiakou, P Sivapalan, K Armbruster… - Clinical Microbiology …, 2022 - Elsevier
Objectives It is unclear whether recurrent sputum culture with Pseudomonas aeruginosa
from patients with chronic obstructive pulmonary disease (COPD) is caused by intermittent …
from patients with chronic obstructive pulmonary disease (COPD) is caused by intermittent …
The problems of antibiotic resistance in cystic fibrosis and solutions
C López-Causapé, E Rojo-Molinero… - Expert review of …, 2015 - Taylor & Francis
Chronic respiratory infection is the main cause of morbidity and mortality in cystic fibrosis
(CF) patients. One of the hallmarks of these infections, led by the opportunistic pathogen …
(CF) patients. One of the hallmarks of these infections, led by the opportunistic pathogen …
Omics-based tracking of Pseudomonas aeruginosa persistence in “eradicated” cystic fibrosis patients
Whenever Pseudomonas aeruginosa is cultured from cystic fibrosis (CF) patient airways, the
primary goal is eradication by antibiotic therapy. Success is defined by≥ 6 months of …
primary goal is eradication by antibiotic therapy. Success is defined by≥ 6 months of …
Epidemiology of infection and current guidelines for infection prevention in cystic fibrosis patients
K Schaffer - Journal of Hospital Infection, 2015 - Elsevier
The spectrum of bacterial pathogens encountered in cystic fibrosis (CF) lung disease has
expanded over the last decade. In addition to established pathogens, such as …
expanded over the last decade. In addition to established pathogens, such as …
Alkyl-quinolone-dependent quorum sensing controls prophage-mediated autolysis in Pseudomonas aeruginosa colony biofilms
G Giallonardi, M Letizia, M Mellini… - Frontiers in Cellular …, 2023 - frontiersin.org
Pseudomonas aeruginosa is a model quorum sensing (QS) pathogen with three
interconnected QS circuits that control the production of virulence factors and antibiotic …
interconnected QS circuits that control the production of virulence factors and antibiotic …