The combined toxicological assessment provides a realistic approach for hazard evaluation
of chemical cocktails that co-existed in the environment. This review provides a holistic …

Background Diethyl phthalate (DEP) is widely used in many commercially available
products including plastics and personal care products. DEP has generally not been found …

The escalating prevalence of male infertility and decreasing trend in sperm quality have
been correlated with rapid industrialisation and the associated discharge of an excess of …

This study evaluated the acute developmental toxicity of six priority phthalic acid esters
(PAEs) including dimethyl phthalate (DMP), diethyl phthalate (DEP), dibutyl phthalate (DBP) …

Great attention has been paid in recent years to the harmful effects of various chemicals that
interfere with our natural hormone balance, collectively known as endocrine-disrupting …

Phthalate esters (PAEs) pose prominent ecological risks owing to their multiplex toxicity
potentials and ubiquitous detection in the environment. Therefore, this study aims to …

In the past 50 years, testosterone (T) level in men has declined gradually. In this research,
we discovered that acute exposure to 1-nitropyrene (1-NP), an environmental stressor from …

Perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic (PFOS) are two perfluorinated
chemical products widely existing in the environment. Evidence suggested that PFOA might …

Testicular dysgenesis syndrome in male neonates manifests as cryptorchidism and
hypospadias, which can be mimicked by in utero phthalate exposure. However, the …

Phthalates are widely used in polymer materials as a plasticizer. These compounds possess
potent toxic variations depending on their chemical structures. However, a growing body of …