The presence of barriers, such as the blood–brain barrier (BBB) and brain–tumor barrier
(BTB), limits the penetration of antineoplastic drugs into the brain, resulting in poor response …

Over various scientific fields in biochemistry, amino acids have been highlighted in research
works. Protein, peptide-and amino acid-based drug delivery systems have proficiently …

Early diagnosis can effectively improve the survival of glioblastoma multiforme (GBM). A
specific imaging technique that is simultaneously deep penetrating and sensitive to small …

In recent years, nano-based drug delivery systems have gradually been regarded as a
promising approach to improve the current glioblastoma treatment, attracting many …

Glioblastoma, also referred to as glioblastoma multiforme (GBM), is grade IV astrocytoma
characterized by being fast-growing and the most aggressive brain tumor. In adults, it is the …

Background Glioblastoma (GBM) is the most common and fatal primary tumor in the central
nervous system (CNS). Due to the existence of blood–brain barrier (BBB), most therapeutics …

Glioblastoma (GBM) is the most common and aggressive primary malignant brain tumor and
is characterized by high mortality and morbidity rates and unpredictable clinical behavior …

According to the difference in temperature, thermotherapy can be divided into thermal
ablation and mild hyperthermia. The main advantage of thermal ablation is that it can …

Introduction High-grade gliomas (HGG) are the most common malignant primary brain
tumors in adults, with a median survival of~ 18 months. The standard of care (SOC) is …

Background: Immunotherapy is changing the way we treat cancer. Immunogenic cell death
(ICD) has received considerable attention in the treatments of various cancer types, due to …