The concept of folic acid in health and disease

Y Shulpekova, V Nechaev, S Kardasheva, A Sedova… - Molecules, 2021 - mdpi.com
Folates have a pterine core structure and high metabolic activity due to their ability to accept
electrons and react with O-, S-, N-, C-bounds. Folates play a role as cofactors in essential …

Stress-induced perinatal and transgenerational epigenetic programming of brain development and mental health

O Babenko, I Kovalchuk, GAS Metz - Neuroscience & Biobehavioral …, 2015 - Elsevier
Research efforts during the past decades have provided intriguing evidence suggesting that
stressful experiences during pregnancy exert long-term consequences on the future mental …

Epigenetic inheritance: concepts, mechanisms and perspectives

I Lacal, R Ventura - Frontiers in molecular neuroscience, 2018 - frontiersin.org
Parents' stressful experiences can influence an offspring's vulnerability to many pathological
conditions, including psychopathologies, and their effects may even endure for several …

[HTML][HTML] Folate and DNA methylation: a review of molecular mechanisms and the evidence for folate's role

KS Crider, TP Yang, RJ Berry, LB Bailey - Advances in nutrition, 2012 - Elsevier
ABSTRACT DNA methylation is an epigenetic modification critical to normal genome
regulation and development. The vitamin folate is a key source of the one carbon group …

The first thousand days: an evidence paper

T Moore, N Arefadib, A Deery, S West - 2017 - research.monash.edu
This paper takes a comprehensive look at the latest evidence regarding the significance of
the first 1000 days, and the biological, global, environmental and social factors that influence …

Cardiometabolic risk in obese children

ST Chung, AU Onuzuruike… - Annals of the New York …, 2018 - Wiley Online Library
Obesity in childhood remains a significant and prevalent public health concern. Excess
adiposity in youth is a marker of increased cardiometabolic risk (CMR) in adolescents and …

Environment and brain plasticity: towards an endogenous pharmacotherapy

A Sale, N Berardi, L Maffei - Physiological reviews, 2014 - journals.physiology.org
Brain plasticity refers to the remarkable property of cerebral neurons to change their
structure and function in response to experience, a fundamental theoretical theme in the …

Toxic stress in children and adolescents

M Bucci, SS Marques, D Oh… - Advances in …, 2016 - advancesinpediatrics.com
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The contribution of maternal stress to preterm birth: issues and considerations

PD Wadhwa, S Entringer, C Buss… - Clinics in …, 2011 - perinatology.theclinics.com
Preterm birth represents the most significant problem in maternal–child health in the United
States. It is the leading cause of infant mortality and morbidity; its prevalence is unacceptably …

Prenatal stress and brain development

A Charil, DP Laplante, C Vaillancourt, S King - Brain research reviews, 2010 - Elsevier
Prenatal stress (PS) has been linked to abnormal cognitive, behavioral and psychosocial
outcomes in both animals and humans. Animal studies have clearly demonstrated PS effects …